Results 61 to 70 of about 4,029,223 (268)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
International Journal of Modern Physics D, 2011 I review the definition and types of (closed) trapped surfaces. Surprising global properties are shown, such as their "clairvoyance" and the possibility that they enter into flat portions of the spacetime. Several results on the interplay of trapped surfaces with vector fields and with spatial hypersurfaces are presented.
openaire +2 more sources
Fullerenes as adhesive layers for mechanical peeling of metallic, molecular and polymer thin films
Beilstein Journal of Nanotechnology, 2014 We show that thin films of C60 with a thickness ranging from 10 to 100 nm can promote adhesion between a Au thin film deposited on mica and a solution-deposited layer of the elastomer polymethyldisolaxane (PDMS).
Maria B. Wieland +4 more
doaj +1 more source
Acta Geographica Slovenica, 2005 Studying relief and landscapes, we often employ digital elevation models. Their applicability is primarily linked to their accuracy. In this paper, we compare the older 100-meter digital elevation model of Slovenia and the more recent 25-meter digital ...
Mauro Hrvatin, Drago Perko
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Proceedings of the twenty-second annual symposium on Computational geometry, 2006 We construct a class of envelope surfaces in Rd, more precisely envelopes of balls. An envelope surface is a closed C1 (tangent continuous) manifold wrapping tightly around the union of a set of balls. Such a manifold is useful in modeling since the union of a finite set of balls can approximate any closed smooth manifold arbitrarily close.
Kruithof, Nico, Vegter, Gert
openaire +2 more sources
Contact fatigue phenomena in back-up rolls of alloyed steels
Metalurgija, 2017 The improvement of back-up rolls properties in terms of wear resistance is driven by the need of longer and longer rolling sessions aimed to increase productivity and reduce costs. Chemical composition effect on contact fatigue phenomena, bringing to the
P. E. Di Nunzio, A. Di Schino
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The effect of condition of the charge surface on the scale adhesion for excess air combustion
Metalurgija, 2015 In the process of heating steel the processes of chemical interaction occur between the furnace atmosphere and the surface of the steel being heated. Great importance, in aspect of course of the oxidizing process equal as well as for phenomenon of scale ...
J. Boryca, T. Wyleciał, D. Urbaniak
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source