Results 71 to 80 of about 4,029,223 (268)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
THE STRUCTURE OF MONOATOMIC LAYER ON GRAPHITE SURFACE
Monatomic surface layers of graphite were simulated on the basis of experimental data, which was obtained by scanning tunneling electron microscopy of atomically smooth surface of graphite.
V. G. Kirichenko, A. A. Yampolskiy
doaj
Recently, coated paper substrates have been used in a wide range of packaging applications. In this research, we present a chitosan with rosemary essential oil, paper coating as water and possible repellent resistant solution on biological basis. The aim
Urška Vrabič Brodnjak, Katarina Tihole
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Biochips: Focusing on Surfaces and Surface Modification
Thousands of genes and their products (i.e., proteins) in a given living organism function in a complicated and orchestrated way that creates the mystery of life. In “genomics”, briefly genes of organisms, their functions and activities are investigated.
Piskin, E, Garipcan, B
openaire +4 more sources
Evaluation of the impact energy of the samples produced by the additive manufacturing technology
The article covered the evaluation of the impact energy, notch toughness and morphology of the fracture surfaces of the specimens manufactured by the Direct Metal Laser Sintering Technology.
J. Dobránsky +6 more
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
AbstractOn‐surface synthesis constitutes a rapidly growing field of research due to its promising application for creating stable molecular structures on surfaces. While self‐assembled structures rely on reversible interactions, on‐surface synthesis provides the potential for creating long‐term stable structures with well‐controlled properties, for ...
Lindner, Robert, Kühnle, Angelika
openaire +3 more sources
The corrosion resistant coating with halloysite nanoparticles
The process of application of coating on metal surfaces is described in this article. The composition with 100 % corrosion preventing substance + 42,5 % acetone + 10 % halloysite was recognized as the most appropriate for coating, and it provides the ...
A. Z. Issagulov +4 more
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

