Results 121 to 130 of about 1,650,006 (287)

Diffusion pump modification promotes self-cleansing and high efficiency [PDF]

open access: yes, 1975
Modifications eliminate contaminant substances from pump fluid during operation, which are principal causes of torpidity on evaporative surface. Diffusion pump is also acting as still.
Buggele, A. E.
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Effect of Emotional Labor Strategies over Job Performance with Emotional Exhaustion Mediating [PDF]

open access: yesمطالعات مدیریت راهبردی, 2014
Because of continuous increase in economics and contests among service providers, management of emotions in the workplace is becoming really important. Surface and deep acting as strategies of emotional labor are presented by which people try to control ...
Seyyedeh Mansoureh Hosseini Robat   +1 more
doaj  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Beyond surface and deep acting: investigating interaction avoidance in coworkers’ daily relationships and its consequences

open access: yesWork & Stress
Research on emotional labour toward coworkers focused on surface acting and deep acting, thereby applying the knowledge on emotional labour in service but neglecting specific features of coworkers’ relationships. Addressing this issue, we develop and test a conceptual model in which surface acting and deep acting are complemented by another behavioural
Shoshan, Hadar Nesher   +2 more
openaire   +5 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Postseismic surface deformations due to lithospheric and asthenospheric viscoelasticity [PDF]

open access: yes
A model is proposed for post seismic surface deformations attributing them to lithospheric and asthenospheric viscoelasticity. The model predicts that the deformations due to lithospheric viscoelasticity depend on the ratio of the effective shear modulus
Cohen, S. C.
core   +1 more source

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