Results 111 to 120 of about 1,267,460 (349)

Iron oxide nanoparticles and derivatives for biomedical imaging and application in cancer diagnosis and siRNA therapy [PDF]

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011), Medarova, Z, Yigit, MV   +2 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Nanoencapsulation of ultra-small superparamagnetic particles of iron oxide into human serum albumin nanoparticles

Beilstein Journal of Nanotechnology, 2014
Human serum albumin nanoparticles have been utilized as drug delivery systems for a variety of medical applications. Since ultra-small superparamagnetic particles of iron oxide (USPIO) are used as contrast agents in magnetic resonance imaging, their ...
Matthias G. Wacker, Mahmut Altinok, Stephan Urfels, Johann Bauer   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Optimization of cleansing oil formulation containing polyglyceryl-6 caprylate and polyglyceryl-4 caprate using the response surface method

İstanbul Journal of Pharmacy
Background and Aims: Natural raw materials used in skin cleansing products have recently become popular. In this study, natural-origin raw materials were used to develop an oil-based cleanser formulation with high foaming ability and stable properties ...
Ayşenur Kılıç, Burak Çelik
doaj   +1 more source

Herbicide Adjuvants in Citrus Weed Control

EDIS, 2022
Adjuvants are materials added into a herbicide spray mix that improves the herbicide’s performance, especially its handling, application efficacy, and crop-safety.
Ramdas Kanissery
doaj  

Preparation and surface active properties of a-acyloxysuccinic acid derivatives from malic acid and fatty acids of crude rice bran oil

Grasas y Aceites, 2000
Surface active compounds were prepared from malic acid by esterification with acyl chloride (II)a-d, of [palmitic, stearic, oleic, linoleic and mixed fatty acids of rice bran oil (RBO) (II)e], in the presence of pyridine as catalyst, forming (III)a-e ...
W. I.A. EL-Dougdoug, K. A.H. Hebash, A. A. El-Sawy   +2 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Lattice QCD Thermodynamics on the Grid

, 2009
We describe how we have used simultaneously ${\cal O}(10^3)$ nodes of the EGEE Grid, accumulating ca. 300 CPU-years in 2-3 months, to determine an important property of Quantum Chromodynamics.
de Forcrand, de Forcrand, de Forcrand, de Forcrand, de Forcrand, de Forcrand, Ferrenberg, Germain-Renaud, Jakub T. Mościcki, Karsch, Kim, Maciej Woś, Massimo Lamanna, Mitchel, Mościcki, Owe Philipsen, Philippe de Forcrand, Roberge   +17 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source