Results 101 to 110 of about 12,679,538 (309)
Sequential analysis of surfactant, lung function and inflammation in cystic fibrosis patients
Background In a cross-sectional analysis of cystic fibrosis (CF) patients with mild lung disease, reduced surfactant activity was correlated to increased neutrophilic airway inflammation, but not to lung function.
Paul Karl +6 more
doaj +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Photocatalytic activity of the overall H2O splitting on Ga2O3 enhanced by surface-phase junction
Photocatalytic activity of the overall H2O splitting on Ga2O3 enhanced by surface-phase ...
徐倩 +5 more
core
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The influence of playing surface on physiological and performance responses during and after soccer simulation [PDF]
The aim of this study was to investigate the effect of playing surface on physiological and performance responses during and in the 48 h after simulated soccer match play.
Newcombe, Daniel J. +5 more
core +1 more source
Wood Gasification Biochar as an Effective Biosorbent for the Remediation of Organic Soil Pollutants
A biochar (BC) generated by the pyrogasification of wood chips from authorized forestry cuts was extensively characterized and evaluated for its efficacy in retaining/releasing two agrochemicals, namely the fungicide penconazole (PEN), the herbicide S ...
Elisabetta Loffredo +5 more
doaj +1 more source

