Results 81 to 90 of about 30,742,917 (357)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Effect of different surface preparations prior to painting on the corrosion behaviour and surface activity of mild steel [PDF]
Previous work in our laboratory showed that the type of surface preparation of the steel prior to coating had a dramatic effect on the subsequent corrosion protection afforded in immersion tests and in salt spray testing.
Mills, Douglas J; id_orcid +2 more
core
The objective of the study was to detect volcanic activity at different timescales using geostationary satellite derived Land Surface Temperature data.
Pavlidou, E. (Faculty of Geo-Information Science and Earth Observation (ITC), University of Twente), Researcher
core +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Syndecan-4 regulates cell-surface trafficking and biological activity of transglutaminase-2 [PDF]
Transglutaminase-2 (TG2) is a Ca2+-dependent crosslinking enzyme involved in the post-translational modification of proteins via the formation of Nε(γ-glutamyl)lysine isodipeptides.
Scarpellini, A
core
The Activity of Surfaces [PDF]
IN recent years a good deal of attention has been given to the relation between the catalytic effect of a surface and its structure, and in this connexion it is perhaps of interest to point out that the general idea underlying many theories was published by me in 1911 (J. Chem. Soc., 475 ff., 1911) in a qualitative form.
openaire +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
SURFACE ACTIVITY AND OSCILLATION AMPLITUDES OF RED GIANTS IN ECLIPSING BINARIES [PDF]
Among the 19 red-giant stars belonging to eclipsing binary systems that have been identified in Kepler data, 15 display solar-like oscillations. We study whether the absence of mode detection in the remaining 4 is an observational bias or possibly ...
P. Gaulme +3 more
semanticscholar +1 more source
Adsorption and Aggregation Behaviors of Oleyl Alcohol-Based Extended Surfactant and Its Mixtures
An oleyl alcohol-based extended surfactant, sodium oleyl polyethylene oxide-polypropylene oxide sulfate (OE3P3S), was synthesized and identified using FT-IR and 1H NMR.
Ping Li +6 more
doaj +1 more source

