Results 61 to 70 of about 11,059 (260)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Sensors, 2023 With the increasing depletion of shallow coal resources, deep roadway excavation has become the main direction in the development of coal mining. Due to geological conditions including high stress and extremely broken rock, disasters such as squeezing ...
Lei Wang, Wei Lu
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Fusing catechol-driven surface anchoring with rapid hetero diels-alder ligation
, 2014 We fuse the surface anchoring abilities of catechols with the rapid ligating nature of thiocarbonyl thio-based hetero-Diels-Alder (HDA) reactions via the synthesis of a new small molecule (HDA-DOPA-Cp) combining a HDA moiety with a catechol.
Preuss, C. M. +9 more
core +1 more source
Frontiers in Soft Matter, 2023 This review presents an integrated theoretical and computational characterization and analysis of surface pattern formation in chiral and achiral liquid crystal self-assembly and the mechanical/optical/tribological/tissue engineering surface ...
Ziheng Wang +3 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Development of a Landing Mechanism for Asteroids with Soft Surface
International Journal of Aerospace Engineering, 2013 A landing mechanism to an asteroid with soft surface is developed. It consists of three landing feet, landing legs, cardan element, damping element, equipment base, anchoring system, and so on.
Zhijun Zhao, Jingdong Zhao, Hong Liu
doaj +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Optical Studies of Ordered Monomolecular Layers: Ab Initio Simulation and Experiment [PDF]
, 2009 Due to the general interest on the alignment effect of the surface-bound ultrathin layers, this thesis presents research of the investigation of anchoring properties for liquid crystal (LC) molecules adsorbed on a solid substrate, using dual polarization
TAN, ZHENG
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source