Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle [PDF]
, 2017 Eimeria spp. are intracellular parasites that have a major impact on poultry. Effective live vaccines are available and the development of reverse genetic technologies has raised the prospect of using Eimeria spp.
Blake, D P +4 more
core +1 more source
Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers. [PDF]
PLoS ONE, 2011 Antibodies to polymorphic antigens expressed during the parasites erythrocytic stages are important mediators of protective immunity against P. falciparum malaria.
Louise Turner +6 more
doaj +1 more source
Liposome-coupled antigens are internalized by antigen-presenting cells via pinocytosis and cross-presented to CD8 T cells. [PDF]
PLoS ONE, 2010 We have previously demonstrated that antigens chemically coupled to the surface of liposomes consisting of unsaturated fatty acids were cross-presented by antigen-presenting cells (APCs) to CD8+ T cells, and that this process resulted in the induction of
Yuriko Tanaka +4 more
doaj +1 more source
New immunolatex spheres: visual markers of antigens on lymphocytes for scanning electron microscopy [PDF]
, 1975 New immunochemical reagents consisting of antibodies bound to small latex spheres were used as visual markers for the detection and localization of cell surface antigens by scanning electron microscopy.
Dreyer, William J. +3 more
core +2 more sources
Systematic Review: Syndromes, Early Diagnosis, and Treatment in Autoimmune Encephalitis
Frontiers in Neurology, 2018 In recent years, new antibodies have been discovered which mediate autoimmune encephalitis. This immunological response can be triggered by an infection or a tumor.
Christina Hermetter +2 more
doaj +1 more source
The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies. [PDF]
, 2016 Central to the humoral theory of transplantation is production of antibodies by the recipient against mismatched HLA antigens in the donor organ. Not all mismatches result in antibody production, however, and not all antibodies are pathogenic.
Farber, John, Filippone, Edward J
core +4 more sources
Human natural killer cell committed thymocytes and their relation to the T cell lineage. [PDF]
, 1993 Recent studies have demonstrated that mature natural killer (NK) cells can be grown from human triple negative (TN; CD3-, CD4-, CD8-) thymocytes, suggesting that a common NK/T cell precursor exists within the thymus that can give rise to both NK cells ...
Lanier, LL +3 more
core +1 more source
The MDM-2 Antagonist Nutlin-3 Promotes the Maturation of Acute Myeloid Leukemic Blasts
Neoplasia: An International Journal for Oncology Research, 2007 The small-molecule inhibitor of murine double minute (MDM-2), Nutlin-3, induced variable apoptosis in primary acute myeloid leukemia (AML) blasts, promoted myeloid maturation of surviving cells, as demonstrated by analysis of CD11 b, CD14 surface ...
Paola Secchiero +7 more
doaj +1 more source
Molecular mechanisms and biological importance of Plasmodium falciparum erythrocyte rosetting
Memorias do Instituto Oswaldo Cruz, 1992 Rosetting, i.e. the spontaneous binding of uninfected to malaria infected erythrocytes and endothelial cytoadherence may hinder the blood flow and lead to serve Plasmodium falciparum malaria.
Mats Wahlgren +4 more
doaj +1 more source
TCR-T immunotherapy for the treatment of solid tumor: current status, challenges and future prospects [PDF]
Zhongguo aizheng zazhi, 2023 Engineered T cell receptor-T cell (TCR-T) therapy and chimeric antigen receptor-T cell (CAR-T) therapy are currently the two most effective ways of adoptive T cell therapy.
ZHENG Weitao, LI Hanluo, HU Kanghong
doaj +1 more source