Results 271 to 280 of about 607,266 (334)

IL‐2 Free Expansion of T Cells with Immunofilaments

Advanced Healthcare Materials, EarlyView.
Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck, Lea Weiss, René Classens, Carl G. Figdor, Roel Hammink   +4 more
wiley   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Evaluation of larval surface antigens from infective larvae of Strongyloides venezuelensis for the serodiagnosis of human strongyloidiasis. [PDF]

Rev Inst Med Trop Sao Paulo
europepmc   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Redevelopment of hepatitis B surface antigen after renal transplantation

, 1991
Patrick Marcellin, Emile Giostra, Michèle Martinot‐Peignoux, Marie‐Anne Loriot, Marie-Lorraine Jaegle, Philippe Wolf, Claude Degott, Françoise Degos, Jean‐Pierre Benhamou   +8 more
openalex   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan, Bence Bajusz, Norbert Fabók, Marina Rudan Dimlic, Jelena Budimir, Tshepang Mqatywa, Miklós Gyöngy, Márton Ferencz, Dorottya Kocsis, Olexandr Bondarenko, Mariia Rolduhina, Milena Lengyel, Istvan Antal, Rebecca Hengsbach, Franciska Erdő, Amir Fahmi   +15 more
wiley   +1 more source

Absence of Autoantibodies Against Neuronal Surface Antigens in Sera of Patients With Psychotic Disorders.

JAMA Psychiatry, 2020
Hoffmann C, Zong S, Mané-Damas M, Molenaar PC, Losen M, Titulaer MJ, Martinez-Martinez P, European Consortium of Autoimmune Mental Disorders.   +7 more
europepmc   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source