Results 241 to 250 of about 302,410 (282)

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

Advanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider, Alexander Fuchs, Michael Fichter, Vanessa Bolduan, Jenny Schunke, Özlem Akilli, Nádia C. Correia, Yannick Ehlers, Christian Czysch, Pia Winterwerber, Eliana Stanganello, Barbara Schrörs, Mustafa Diken, Christoph Eckert, Shusruto Rishik, Andreas Keller, Jörn M. Schattenberg, Stephan Grabbe, Matthias Bros, Lutz Nuhn, Leonard Kaps   +20 more
wiley   +1 more source

Highlighting the Importance of His Bundle Potential During Tachycardia and Ventricular Overdrive Pacing. [PDF]

J Arrhythm
Matsunaga-Lee Y, Egami Y, Yasumoto K, Yano M, Nishino M.   +4 more
europepmc   +1 more source

Overcoming resistance in advanced urothelial carcinoma: mechanisms of escape from antibody-drug conjugates and FGFR3 inhibition. [PDF]

Front Oncol
Wummer B, Schwartz M, Ciuro J, Ahmed S, Joshi SS, Narayan VM, Carthon BC, Bilen MA, Brown JT.   +8 more
europepmc   +1 more source

Endoscopic versus open vein harvesting for coronary artery bypass: a systematic review and meta-analysis. [PDF]

J Cardiothorac Surg
Arnaout AY, Aladna A, Kozum R, Makki R, Sabouni A, Antakli K, Raffoul L, Shabouk MB, Nayal S, Arnaout K, Amino A.   +10 more
europepmc   +1 more source

Medication Adjustment After Bariatric and Metabolic Surgery: A Review of Current Evidence and Clinical Practice Trends. [PDF]

J Metab Bariatr Surg
Park JH, Kim S, Seo HS, Song KY, Lee HH.
europepmc   +1 more source

Initiators counteract Polycomb repression and stimulate long-range contacts between enhancers and the <i>Abdominal-B</i> promoter in <i>Drosophila</i>. [PDF]

Open Biol
Kyrchanova O, Kudryashova K, Dubrovskaya V, Ibragimov A, Schedl P, Georgiev P.   +5 more
europepmc   +1 more source

"Brake" and "accelerator": revisiting tumor cell direct responses and the paradox of aggression in anti-VEGF therapy. [PDF]

Front Immunol
Wei P, Li J, Cheng X, Lu Y, Xia Q, Wang Z.   +5 more
europepmc   +1 more source

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High Frequency Surface Heat Flux Imaging of Bypass Transition

Volume 4: Turbo Expo 2004, 2004
A high-frequency surface heat flux imaging technique was used to investigate bypass transition induced by freestream turbulence. Fundamental experiments were carried out at the University of Oxford using high-density thin film arrays on a flat plate wind tunnel model.
Richard J. Anthony, Terry V. Jones, John E. LaGraff   +2 more
openaire   +1 more source