Results 71 to 80 of about 6,291,331 (296)

Surface-Charge-Driven Ferroptosis and Mitochondrial Dysfunction Is Involved in Toxicity Diversity in the Marine Bivalve Exposed to Nanoplastics

Nanoplastics (NPs) pervade daily life, posing serious threats to marine ecosystems. Despite the crucial role that surface charge plays in NP effects, there is a substantial gap in our understanding of how surface charge influences NP toxicity. Herein, by
Hao Jiang (95017), Xiao-Xia Zhou (1461487), Wenzhi Liu (3997184), Yanfei Zhou (704684), Jorge L. Gardea-Torresdey (1455463), Fengyuan Chen (771754), Yanping Li (90163), Bing Yan (170259)   +7 more
core   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Surfaces Designed for Charge Reversal

Journal of the American Chemical Society, 2003
We have created surfaces which switch from cationic at pH < 3 to anionic at pH > 5, by attaching aminodicarboxylic acid units to silica and gold substrates. Charge reversal was demonstrated by monitoring the adsorption of cationic dyes (methylene blue and a tetracationic porphyrin) and an anionic sulfonated porphyrin, at a range of pH using UV-vis ...
Matthews, JR, Tuncel, D, Jacobs, R, Bain, C, Anderson, H   +4 more
openaire   +2 more sources

Surface charge visualization at viable living cells

, 2016
Scanning ion conductance microscopy (SICM) is demonstrated to be a powerful technique for quantitative nanoscale surface charge mapping of living cells.
Ashley Page (2342770), Philip D. Voyias, Paulose Nadappuram, Binoy, Voyias, Philip D., Dmitry Momotenko (1408444), Frenguelli, B.G, Dmitry Momotenko, Unwin, P.R, Bruno G. Frenguelli (2342776), David Perry (358135), Voyias, P.D., Momotenko, D., Momotenko, Dmitry, Page, Ashley M., Philip D. Voyias (2342773), Ashley Page, Tripathi, G, Bruno G. Frenguelli, Binoy Paulose Nadappuram (1298685), Patrick R. Unwin (1298697), Binoy Paulose Nadappuram, Tripathi, G., Momotenko, D, Paulose Nadappuram, B., Unwin, P.R., Voyias, P.D, David Perry, Unwin, Patrick R., Perry, D., Patrick R. Unwin, Gyanendra Tripathi, Paulose Nadappuram, B, Page, A, Tripathi, Gyanendra, Perry, David, Frenguelli, Bruno G., Frenguelli, B.G., Gyanendra Tripathi (350027), Page, A., Perry, D   +39 more
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Measurement of surface potential decay of corona-charged polymer films using the pulsed electroacoustic method

, 2007
In this paper, the pulsed electroacoustic (PEA) technique that allows the determination of space charge in a dielectric material has been used to monitor the electrical potential decay of corona-charged polyethylene films of different thicknesses.
Xu, Z, Chen, G, Zhang, L W
core   +1 more source

Spontaneous Imbibition and an Interface-Electrostatics-Based Model of the Transition Zone Thickness of Hydrocarbon Reservoirs and Their Theoretical Interpretations

AppliedMath
The transition zone (TZ) of hydrocarbon reservoirs is an integral part of the hydrocarbon pool which contains a substantial fraction of the deposit, particularly in carbonate petroleum systems.
Mumuni Amadu, Adango Miadonye
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A surface-charge model for mudstones and the application to Pore Pressure Prediction [PDF]

, 2005
New geologic concepts have been developed that illuminate the critical role of bound water in the generation and prediction of overpressures in mudstones.
Traugott, Martin Olson
core