Results 51 to 60 of about 6,001,475 (296)

Antigen/adjuvant‐free liposome induces adjuvant effects for enhancing cancer immunotherapy

open access: yesExploration
Cancer vaccines are promising to treat malignancy by delivering antigens and adjuvants to elicit host immunity. Beyond aluminum adjuvants, liposomes show efficient adjuvant effects through regulating the accumulation, internalization and release of ...
Qianqian Guo   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Charge transport mechanisms in corona charged polymeric materials

open access: yes, 2013
Polymeric materials have been widely used as an insulator due to their excellent electrical properties, light weight and low cost. Surface potential measurement is one of the simplest and low cost tools to gauge electrical properties of materials.
Zhuang, Yuan
core   +1 more source

Adsorption of polyampholytes on charged surfaces [PDF]

open access: yesThe European Physical Journal E, 2002
We have studied the adsorption of neutral polyampholytes on model charged surfaces that have been characterized by contact angle and streaming current measurements. The loop size distributions of adsorbed polymer chains have been obtained using atomic force microscopy (AFM) and compared to recent theoretical predictions. We find a qualitative agreement
Ozon, F., Meglio, J.-M., Joanny, J.-F.
openaire   +4 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Temperature effect on space charge dynamics in XLPE insulation [PDF]

open access: yes, 2007
This paper reports on space charge evolution in crosslinked polyethylene (XLPE) planar samples approximately 1.20 mm thick subjected to electric stress level of 30 kVdc/mm under four temperature 25 oC, 50 oC, 70 oC and 90 oC for 24 hours.
Chong, Y L, Chen, G, Ho, Y F F
core   +2 more sources

Space charge dynamics in low density polyethylene under dc electric fields

open access: yes, 2007
In this paper space charge dynamics in low-density polyethylene (LDPE) under different dc electric fields, ranging from 25 kV/mm to 125 kV/mm, have been investigated using the pulsed electroacoustic (PEA) technique. Bipolar space charges have been formed
Xu, Zhiqiang, Chen, George
core   +2 more sources

Surface Complexes of Cr(VI) by Eucalyptus Barks

open access: yesIndonesian Journal of Chemistry, 2022
The sorption mechanism of hexavalent chromium sorption on eucalyptus barks was evaluated as a function of solution pH for different adsorbent dosages, surface coverage, and the amount of adsorbent.
Hind Khalil   +7 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

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