Results 61 to 70 of about 40,177 (246)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Sorption of tetravalent U(IV) on MX-80 and granite in Ca-Na-Cl solutions under reducing conditions
Nuclear Engineering and TechnologyUranium has been identified as an element of interest for the safety assessment of a deep geological repository (DGR) for used nuclear fuel. This paper studied the sorption behavior of tetravalent U(IV) onto MX-80 bentonite and granite in ionic strength ...
Shinya Nagasaki +4 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Contribution of Ternary Reaction to Pd Sorption on MX-80 in Na-Ca-Cl Solution at High Ionic Strength
Science and Technology of Nuclear Installations, 2019 In this study, we first examined the sorption of Pd on MX-80 in Na-Ca-ClO4 solution as a function of pHc (3–9) and ionic strength (0.1 M–4 M) and confirmed that the experimentally derived Kd values could be fitted by a 2-site protolysis nonelectrostatic ...
Shinya Nagasaki +2 more
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Sorption of U(IV) on MX-80, illite, shale and limestone in Na-Ca-Cl solutions
Nuclear Engineering and TechnologyUranium has been identified as an element of interest for the safety assessment of a deep geological repository (DGR) for used nuclear fuel. This paper studied the sorption of tetravalent U(IV) onto MX-80 bentonite, illite, shale and limestone in ionic ...
Shinya Nagasaki +4 more
doaj +1 more source
Surface Complexation Modelling for the Quantitative Description of the Adsorption of Biomolecules
Adsorption Science & Technology, 2008 Surface complexation modelling was used to provide a quantitative description of the adsorption of some B vitamins (thiamin, pyridoxine and pyridoxamine) onto a fumed silica surface as a function of pH, ionic strength and sorbate concentration ...
Nataliya M. Vlasova +1 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source