Results 141 to 150 of about 1,097,727 (354)

Intercalation of Lithium into Graphite: Effects of Surface Chemical Composition from First-Principles Simulations

, 2018
Understanding Li+ transfer at graphite-electrolyte interfaces is key to the development of next-generation lithium ion batteries. In this work, we investigate the Li+ kinetics at these interfaces and we elucidate key factors that determine the ion ...
Amit, Samanta, Tuan Anh, Pham, John, Pask, Mitchell, Ong, Kyoung E., Kweon, Vincenzo, Lordi   +5 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A hybrid additive manufacturing platform to create bulk and surface composition gradients on scaffolds for tissue regeneration. [PDF]

Nat Commun, 2021
Sinha R, Cámara-Torres M, Scopece P, Verga Falzacappa E, Patelli A, Moroni L, Mota C.   +6 more
europepmc   +1 more source

Dark aeolian sediments in Martian craters: Composition and sources

, 2011
Our research focuses on the mineralogical characteristics of dark sediment deposits in Martian craters (dunes, dune fields, and sand sheets) and their local sediment sources, carried out on the basis of 70 selected localities.
R. Jaumann, A. Pacifici, Pacifici, A., F. Poulet, Jaumann, Ralf, Tirsch, Daniela, Poulet, F., D. Tirsch   +7 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

JWST Thermal Emission of the Terrestrial Exoplanet GJ 1132b

The Astrophysical Journal Letters
We present thermal emission measurements of GJ 1132b spanning 5–12 μ m obtained with the Mid-Infrared Instrument Low-Resolution Spectrometer on the James Webb Space Telescope.
Qiao Xue, Jacob L. Bean, Michael Zhang, Alexandra Mahajan, Jegug Ih, Jason D. Eastman, Jonathan Lunine, Megan Weiner Mansfield, Brandon Park Coy, Eliza M.-R. Kempton, Daniel Koll, Edwin Kite   +11 more
doaj   +1 more source

Surface nanostructuring of titanium alloy dental screws by 10 keV Ar+ irradiation

Results in Surfaces and Interfaces
The influence of 10 keV Ar+ ion irradiation on the surface topography of Ti–6Al–4V dental screws was investigated. The surface facing the ion beam became uniformly covered with nanoprotrusions, the size of which increased with the ion fluence.
A.E. Ieshkin, K.F. Minnebaev, D.S. Kireev, A.A. Tatarintsev   +3 more
doaj   +1 more source

On the Origin of Reduced Cytotoxicity of Germanium-Doped Diamond-Like Carbon: Role of Top Surface Composition and Bonding. [PDF]

Nanomaterials (Basel), 2021
Zemek J, Jiricek P, Houdkova J, Ledinsky M, Jelinek M, Kocourek T.   +5 more
europepmc   +1 more source