Results 131 to 140 of about 7,471,443 (306)

A hybrid additive manufacturing platform to create bulk and surface composition gradients on scaffolds for tissue regeneration. [PDF]

Nat Commun, 2021
Sinha R, Cámara-Torres M, Scopece P, Verga Falzacappa E, Patelli A, Moroni L, Mota C.   +6 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

JWST Thermal Emission of the Terrestrial Exoplanet GJ 1132b

The Astrophysical Journal Letters
We present thermal emission measurements of GJ 1132b spanning 5–12 μ m obtained with the Mid-Infrared Instrument Low-Resolution Spectrometer on the James Webb Space Telescope.
Qiao Xue, Jacob L. Bean, Michael Zhang, Alexandra Mahajan, Jegug Ih, Jason D. Eastman, Jonathan Lunine, Megan Weiner Mansfield, Brandon Park Coy, Eliza M.-R. Kempton, Daniel Koll, Edwin Kite   +11 more
doaj   +1 more source

On the Origin of Reduced Cytotoxicity of Germanium-Doped Diamond-Like Carbon: Role of Top Surface Composition and Bonding. [PDF]

Nanomaterials (Basel), 2021
Zemek J, Jiricek P, Houdkova J, Ledinsky M, Jelinek M, Kocourek T.   +5 more
europepmc   +1 more source

Journal of Advanced Composition

, 1983
The Journal of Advanced Composition contains a collection of papers regarding writing and rhetoric: "The JAC is a forum for theory, research and pedagogy regarding (1) those writing courses beyond the freshman courses, excluding technical and creative ...
Lally, Tim D. P., Association of Teachers of Advanced Composition (U.S.)   +1 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Global Distribution of the Key Species on the Surface of Europa

The Astrophysical Journal
The icy surface of Europa is continuously bombarded by ions and electrons from Jupiter’s magnetosphere. The bombardment of the particles dissociates water molecules on the surface of Europa and introduces impurities to the icy surface.
Jiazheng Li, Yinsi Shou, Cheng Li, Xianzhe Jia   +3 more
doaj   +1 more source

Journal of Advanced Composition

, 1981
The Journal of Advanced Composition contains a collection of papers regarding writing and rhetoric: "The JAC is a forum for theory, research and pedagogy regarding (1) those writing courses beyond the freshman courses, excluding technical and creative ...
Lally, Tim D. P., Association of Teachers of Advanced Composition (U.S.)   +1 more
core  

A study of the surface structure and composition of annealed Ga0.96Mn0.04As(100)

, 2004
The surface structure and chemical composition of annealed Ga0.96Mn0.04As(1 0 0) have been studied by scanning tunneling microscopy (STM), auger electron spectroscopy (AES) and low energy electron diffraction (LEED).
Andersen, Jesper N, Kanski, J, Lundgren, Edvin, Gustafson, Johan,, Lundgren, Edvin,, Mikkelsen, Anders, Gustafson, Johan, Mikkelsen, Anders,, Andersen, Jesper N,, Lund University., Sadowski, J   +10 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source