Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Mercury has a very tenuous atmosphere starting at the surface, which is referred to as a surface-bound exosphere, where there are no collisions between exospheric particles.
Peter Wurz +8 more
doaj +1 more source
Role of Surface Phenomena on Converter Slag Composition [PDF]
For beneficiation of converter slag, the role of surface phenomena on slag composition was studied. This work includes some experimental data, which were measured for basic oxygen steel (BOS) slag in Isfahan Steel Plant.
Mohammad Chalkosh Amiri
doaj
SnS2 Nanosheets as a Template for 2D SnO2 Sensitive Material: Nanostructure and Surface Composition Effects. [PDF]
Vasiliev R +8 more
europepmc +1 more source
High-entropy alloys (HEAs) have drawn intensive interest in catalysis owing to their uniquely structured metal sites. However, the composition-dependent near-surface structure of HEAs, which is critical for regulating surface electronic structure and ...
Lei Wang (6656) +6 more
core +1 more source
Radiogenic neodymium composition of surface sediments from the Arctic Ocean
Radiogenic neodymium composition of surface sediments from the Arctic ...
Stein, Ruediger +5 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Effect of Surface Composition on the Selective Capture of Atmospheric CO2 by ZIF Nanoparticles: The Case of ZIF-8. [PDF]
Vendite AC, Soares TA, Coutinho K.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Evaluation of Hydrogen Gettering Rates Correlated to Surface Composition and Texture of Nickel-Plated Zircaloy Getters of Different Heat Treatment Procedures. [PDF]
Rönnebro ECE +5 more
europepmc +1 more source

