Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Influence of Multiple Castings and Surface Treatments on Metal-Ceramic Bond Strength and Surface Composition Variations of Nickel-Chromium (Ni-Cr) Alloy. [PDF]
Chanu LB +5 more
europepmc +1 more source
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Activated Carbon-Supported Pt Catalysts Intended for the Hydroprocessing of Lipid Feedstocks: Effects of Support Surface Composition and Impregnation Protocol. [PDF]
Brandão RD +9 more
europepmc +1 more source
Elucidating the composition of PtAg surface alloys with atomic-scale imaging and spectroscopy
Dipna A. Patel +4 more
openalex +2 more sources
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Effects of diamond nanoparticle surface composition and the sp<sup>3</sup>/sp<sup>2</sup> carbon ratio on tumor proangiogenic potential in vitro. [PDF]
Zawadzka K +8 more
europepmc +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source

