Results 191 to 200 of about 1,097,727 (354)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Effects of diamond nanoparticle surface composition and the sp³/sp² carbon ratio on tumor proangiogenic potential in vitro. [PDF]

Sci Rep
Zawadzka K, Wójcik B, Jaworski S, Ostrowska A, Małolepszy A, Mazurkiewicz-Pawlicka M, Pisarek M, Frączek W, Wierzbicki M.   +8 more
europepmc   +1 more source

Surface Composition and Formulation Heterogeneity of Protein Solids Produced by Spray Drying. [PDF]

Pharm Res, 2019
Wilson NE, Mutukuri TT, Zemlyanov DY, Taylor LS, Topp EM, Zhou QT.   +5 more
europepmc   +1 more source

Equilibrium and dynamics of single-peptide binding to aluminum oxides: Emphasizing the role of local surface charge and hydrophobicity

Understanding the interactions between biomolecules and mineral surfaces is a fundamental challenge at the crossroads of colloid science, surface chemistry, and molecular biophysics.
Lê-Chesnais, Joanne, Rodríguez, Daniela, Lambert, Jean-Francois, Landoulsi, Jessem, Humbert, Cristophe, Méthivier, Christophe   +5 more
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Evolution and Reconstruction of Air-Electrode Surface Composition in Reversible Protonic Ceramic Cells: Mechanisms, Impacts on Catalytic Performance, and Optimization Strategies - A Review. [PDF]

Adv Mater
Shi N, Xie Y, Tadé MO, Shao Z.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Engineering Ti₃C₂-MXene Surface Composition for Excellent Li⁺ Storage Performance. [PDF]

Molecules
Chen M, Fan Q, Yu P, Chen K, Li P, Liang K.   +5 more
europepmc   +1 more source

Correlations between surface composition and aerosolization of jet-milled dry powder inhaler formulations with pharmaceutical lubricants. [PDF]

Int J Pharm, 2019
Mangal S, Park H, Nour R, Shetty N, Cavallaro A, Zemlyanov D, Thalberg K, Puri V, Nicholas M, Narang AS, Zhou QT.   +10 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source