Results 51 to 60 of about 4,863,941 (314)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

The Impact of Air–Sea Flux Parameterization Methods on Simulating Storm Surges and Ocean Surface Currents

Journal of Marine Science and Engineering
As the primary driver of energy transfer between atmospheric and oceanic systems, the air–sea momentum flux fundamentally governs coupled model dynamics through its regulation of wind stress partitioning.
Li Cai, Bin Wang, Wenqian Wang, Xingru Feng   +3 more
doaj   +1 more source

Retrieval of Ocean Surface Radial Velocities With RADARSAT-2 Along-Track Interferometry

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2021
This article provides a detailed presentation of the dual-aperture synthetic aperture radar (SAR) data processing scheme for the retrieval of ocean surface radial velocities.This scheme includes processing of raw SAR data, coregistration of along-track ...
Mamoon Rashid, Christoph H. Gierull
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Assessing the Future ODYSEA Satellite Mission for the Estimation of Ocean Surface Currents, Wind Stress, Energy Fluxes, and the Mechanical Coupling Between the Ocean and the Atmosphere

Remote Sensing
Over the past decade, several studies based on coupled ocean–atmosphere simulations have shown that the oceanic surface current feedback to the atmosphere (CFB) leads to a slow-down of the mean oceanic circulation and, overall, to the so-called eddy ...
Marco Larrañaga, Lionel Renault, Alexander Wineteer, Marcela Contreras, Brian K. Arbic, Mark A. Bourassa, Ernesto Rodriguez   +6 more
doaj   +1 more source

Comparative Study on Assimilating Remote Sensing High Frequency Radar Surface Currents at an Atlantic Marine Renewable Energy Test Site

Remote Sensing, 2017
A variety of data assimilation approaches have been applied to enhance modelling capability and accuracy using observations from different sources. The algorithms have varying degrees of complexity of implementation, and they improve model results with ...
Lei Ren, Michael Hartnett
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Real-time Reconstruction of Surface Velocities from Satellite Observations in the Alboran Sea

Remote Sensing, 2020
Surface currents in the Alboran Sea are characterized by a very fast evolution that is not well captured by altimetric maps due to sampling limitations. On the contrary, satellite infrared measurements provide high resolution synoptic images of the ocean
Jordi Isern-Fontanet, Emilio García-Ladona, José Antonio Jiménez-Madrid, Estrella Olmedo, Marcos García-Sotillo, Alejandro Orfila, Antonio Turiel   +6 more
doaj   +1 more source