Results 71 to 80 of about 140,078 (266)

Direct Ocean Tidal Current Measurements From Space: Enhanced Interpretation of Sentinel‐1 Doppler Shift Signals

open access: yesGeophysical Research Letters
Advances in Sentinel‐1 Doppler processing have continued to unlock deeper understanding of surface current dynamics. With future missions emphasizing total surface currents observations, the resolving of processes will grow, including tidal currents ...
M. G. Hart‐Davis   +4 more
doaj   +1 more source

The Winds and Currents Mission Concept

open access: yesFrontiers in Marine Science, 2019
The Winds and Currents Mission (WaCM) is a proposed approach to meet the need identified by the NRC Decadal Survey for the simultaneous measurements of ocean vector winds and currents. WaCM features a Ka-band pencil-beam Doppler scatterometer able to map
Ernesto Rodríguez   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Combined HF Radar and Drifter Dataset for Analysis of Highly Variable Surface Currents

open access: yesData
This data descriptor presents the HF radar and drifter datasets, along with the methods used to process and apply them in a previously published study on the validation of surface current measurements in a region characterized by highly variable coastal ...
Bartolomeo Doronzo   +4 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Cuencas internacionales y usos sociales del agua: Formación de espacios de cooperación y conflicto: norte de México y oeste de Estados Unidos International Basins and Social Uses of Water: Creation of Spheres of Cooperation and Conflict: North of Mexico and West of the United States

open access: yesSecuencia, 2012
La línea de relación entre México y Estados Unidos tiene diferentes perspectivas de estudio. Pero pocas veces se ha incluido un análisis importante respecto a los usos sociales del agua, así como al contexto que engloba las relaciones de diplomacia por ...
Marco Antonio Samaniego López
doaj  

Topological surface currents accessed through reversible hydrogenation of the three-dimensional bulk. [PDF]

open access: yesNat Commun, 2022
Deng H   +7 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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