Results 121 to 130 of about 37,381 (262)

Recapitulating In Vivo Pharmacokinetics and Size‐Dependent Nanomedicine Delivery in a Microfluidic Platform

Advanced Science, EarlyView.
A microfluidic tumor platform integrates pharmacokinetic flow control, vascular‐like barriers, and 3D tumor spheroids to emulate in vivo drug exposure. The system reproduces dynamic concentration–time profiles and enables size‐dependent nanoparticle transport and efficacy evaluation, providing a predictive framework for assessing nanomedicine ...
Su Jeong Kang, Moon Sup Yoon, Jae Min Lee, Min Jeong Jo, Chae Eun Jin, Dae Hwan Shin   +5 more
wiley   +1 more source

Refractory cor pulmonale under extracorporeal membrane oxygenation for acute respiratory distress syndrome: the role of conversion to veno-pulmonary arterial assist—a case series

Frontiers in Medicine
IntroductionPulmonary vascular dysfunction during severe acute respiratory distress syndrome (ARDS) may lead to right ventricle (RV) dysfunction and acute cor pulmonale (ACP). The occurrence/persistence of ACP despite conventional extracorporeal membrane
François Bagate, François Bagate, Paul Masi, Paul Masi, Madjid Boukantar, Costin Radu, Gabriel Saiydoun, Antonio Fiore, Paul-Matthieu Chiaroni, Emmanuel Teiger, Thierry Folliguet, Romain Gallet, Romain Gallet, Armand Mekontso Dessap, Armand Mekontso Dessap, Armand Mekontso Dessap   +15 more
doaj   +1 more source

Perbandingan Metode International Roughness Index Dan Surface Distress Index (Studi Kasus Ruas Jalan Irigasi Harapan Jaya, Kota Bekasi)

Menara: Jurnal Teknik Sipil
Jalan merupakan sarana penghubung wilayah dengan wilayah lain sehingga tercipta interaksi sosial, ekonomi, dan budaya yang merupakan bagian infrastruktur yang sangat penting dalam mendukung pembangunan ekonomi, politik, sosial budaya, pertahanan dan keamanan.
Ahmad Iqbal, Aulia Choiri Windari, Ribut Nawang Sari   +2 more
openaire   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

Unraveling the optimal strategies for asphalt pavement longevity through preventive maintenance: A case study in South Korea

Case Studies in Construction Materials
This study provides a comprehensive evaluation of three pavement surface treatments—Re-Ascon, Micro-surfacing, and Fog-seal—aimed at enhancing the longevity of asphalt concrete pavement.
Sang-Yum Lee, Jun-Seong Choi, Tri Ho Minh Le   +2 more
doaj   +1 more source

Preoperative FIB‐4 Index as a Potential Factor Associated With Severe Postoperative Complications and Endogenous Organ Failure After Hepatectomy for Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
This study demonstrates that a preoperative FIB‐4 index ≥ 5.0 independently predicts severe complications and endogenous organ failure (EOF) following hepatectomy for hepatocellular carcinoma. By capturing structural liver fragility and systemic vulnerability, the FIB‐4 index enhances surgical risk stratification beyond traditional functional markers ...
Masanori Nakamura, Yukiyasu Okamura, Osamu Aramaki, Nao Yoshida, Yusuke Mitsuka, Hayato Abe, Shunsuke Yamagishi, Yasuhiro Okumura, Kyongsun Pak, Shinobu Masuda   +9 more
wiley   +1 more source

Analysis of Secondary Local Road Conditions Using the Surface Distress Index (SDI) Method in Medan Amplas District

ASTONJADRO
Road network data and information and spatial supporting infrastructure are important to a road database management planning process. Medan Amplas District, Medan City has a road network divided into national authority roads, provincial roads and city roads, which is 143.14 km. The study area in this research is a flexible pavement-type secondary local
Edo Rizki Pradana Lubis, Gina Cynthia Raphita Hasibuan, M. Ridwan Anas   +2 more
openaire   +1 more source

Modular design and supervisory control for enhanced economic resilience in continuous pharmaceutical manufacturing

AIChE Journal, EarlyView.
Abstract Conventional continuous plants use fixed‐capacity equipment, resulting in high capital risk and suboptimal performance under fluctuating demands. To address these, this study proposes an integrated framework for modular process design and supervisory control capable of adapting to demand uncertainty for long‐term economic viability.
T. Asrav, M. Alvarado‐Morales, G. Sin
wiley   +1 more source

AI‐Assisted IoT‐Enabled ECG Monitoring: Integrating Foundational and Generative AI Tools for Sustainable Smart Healthcare—Recent Trends

AI &Innovation, EarlyView.
ABSTRACT The rapid evolution of the Internet of Things (IoT) has significantly advanced the field of electrocardiogram (ECG) monitoring, enabling real‐time, remote, and patient‐centric cardiac care. This paper presents a comprehensive survey of AI assisted IoT‐based ECG monitoring systems, focusing on the integration of emerging technologies such as ...
Amrita Choudhury, Kandarpa Kumar Sarma, Lachit Dutta   +2 more
wiley   +1 more source

The psychosocial toll of Dublin III on asylum seekers in the Netherlands

American Journal of Community Psychology, EarlyView.
Abstract The Dublin III Regulation determines which EU Member State is responsible for examining asylum claims, but its implementation carries significant consequences for those subjected to it. This study examines how Dublin III, as implemented in the Netherlands, affects asylum seekers' psychosocial wellbeing using Silove′s Adaptation and Development
Imen El Amouri
wiley   +1 more source