Results 101 to 110 of about 37,381 (262)

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Toward Autonomous Pavement Inspection: An End-to-End Vision-Based Framework for PCI Computation and Robotic Deployment

Automation
Advancements in robotics and computer vision are transforming how infrastructure is monitored and maintained. This paper presents a novel, fully automated pipeline for pavement condition assessment that integrates real-time image analysis with PCI ...
Nada El Desouky, Ahmed A. Torky, Mohamed Elbheiri, Mohamed S. Eid, Mohamed Ibrahim   +4 more
doaj   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

Advanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang, Yuhang Tang, Ronghao Yue, Jingtao Xu, Yong Tao, Jie Chen, Shipeng Li, Guosheng Zhao, Jinfang Xue, Mingwei Sun, Fenglei Gao, Yunsheng Ou, Yang Wang   +12 more
wiley   +1 more source

Development of A Surface Distress Index Prediction Framework using Artificial Neural Networks for Roads Infrastructure Management

Jurnal Teknologi Transportasi dan Logistik
Road infrastructure is a crucial element of urban development, affecting transportation efficiency and road safety. Conventional techniques for evaluating road conditions often fail to capture the full complexity of deterioration and damage over time. This study explores the potential of Artificial Neural Networks (ANN) in predicting road conditions to
Yogi Oktopianto, Antonius Antonius, Abdul Rochim, Dynes Rizky Navianti, Aswin Badarudin Atmajaya   +4 more
openaire   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

ASSESMENT OF THE WATER QUALITY IN SIRET HYDROGRAPHIC BASIN

Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2019
The current study is focusing on the evaluation of the quality of surface water from the Siret hydrographic basin. For this purpose, was used the Global Pollution Index (I*GP), which was calculated for eleven water sampling points from Siret Basin.
VIOLETA NĂSTUNEAC , SIMONA GAVRILAȘ , FLORENTINA-DANIELA MUNTEANU   +2 more
doaj  

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

Damage Condition Analysis Of Semparuk – Bentunai Road With Surface Distress Index (SDI) And Bina Marga Method

Jurnal Teknik Sipil
Road infrastructure plays a vital role in socio-economic development but is highly prone to deterioration caused by aging, drainage deficiencies, and increasing traffic loads. This study analyzes the damage condition of the Semparuk–Bentunai Road, a 20.7 km Class IIIA district road in Sambas Regency, focusing on a 3.2 km section identified as severely ...
Uray Rima Firmandari, Elsa Tri Mukti, Siti Mayuni   +2 more
openaire   +1 more source

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

Pavement crack detection based on depth-supervision FRRN model

Measurement + Control
Timely detection of early pavement distress is crucial for effective pavement maintenance. A promising approach involves the segmenting the road surface cracks area from its images. However, the previously employed full-resolution residual network (FRRN),
Lei Wang, Qiangqiang Feng, Jiao Yan
doaj   +1 more source