Results 91 to 100 of about 37,520 (301)

Analysis of Road Surface Deterioration Level Using Surface Distress Index and Pavement Condition Index at Jalan Rasau Jaya-Sungai Bulan

open access: yesJurnal Teknik Sipil
Roads are vital infrastructure that plays a role in supporting economic growth, the agricultural sector, and regional development by improving accessibility and smooth transportation. However, high traffic intensity and environmental factors can cause road quality degradation, impacting user safety and comfort.
Muzhaffar Fikri Aqila   +2 more
openaire   +1 more source

ANALISIS TINGKAT KERUSAKAN PERMUKAAN PERKERASAN JALAN MENGGUNAKAN METODE SURFACE DISTRESS INDEX (SDI) DAN PAVEMENT CONDITION INDEX (PCI) PADA RUAS JALAN SOEKARNO HATTA KOTA SANGATTA [PDF]

open access: yes
Jalan adalah sarana infrastruktur yang menghubungkan suatu daerah ke daerah lainnya. Jalan Soekarno Hatta dapat menjadi jalur penting untuk distribusi logistik dan hasil tambang.
Budiman, Ery Budiman   +2 more
core   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Assessment of road pavement conditions using Surface Distress Index (SDI) and Pavement Condition Index (PCI) methods

open access: yesIOP Conference Series: Earth and Environmental Science
Abstract Road pavement is an important element in transportation infrastructure that affects the comfort and safety of road users. It is important to carry out regular assessments of the condition of the road pavement. This study aims to evaluate the condition of the road pavement using the Surface Distress Index (SDI) and Pavement ...
Putu Hermawati, N P A S Putri
openaire   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

open access: yesAdvanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang   +26 more
wiley   +1 more source

A case study on predicting asphalt pavement distress using advanced machine learning techniques and road surface inspection data

open access: yesCase Studies in Construction Materials
This study develops robust machine learning models to predict pavement distress using high-resolution road surface scan data. The dataset includes 4685 samples representing various pavement conditions across different locations.
Abolfazl Yazdi, Mohammad Hosein Dehnad
doaj   +1 more source

ANALISIS DAMPAK REFOCUSING ANGGARAN TERHADAP KONDISI JALAN DENGAN METODE SURFACE DISTRESS INDEX (SDI)

open access: yesINFOMANPRO, 2023
Pemerintah Indonesia telah melakukan berbagai upaya untuk menangani penyakit menular yang disebabkan oleh virus SARS-CoV-2 ini, salah satunya melalui Instruksi Presiden Republik Indonesia No. 4 tahun 2020 tentang Refocussing Kegiatan, Realokasi Anggaran, Serta Pengadaan Barang dan Jasa Dalam Rangka Percepatan Penanganan Corona Virus Disease 2019 (Covid-
openaire   +1 more source

ANALISIS KERUSAKAN JALAN DENGAN MENGGUNAKAN METODE SURFACE DISTRESS INDEX (SDI) DAN BINA MARGA (Studi Kasus : Jalan Yos Sudarso Manado 0+000 – 2+500) [PDF]

open access: yes, 2022
Jalan merupakan suatu sarana bagi transportasi untuk memenuhi kebutuhannya masing-masing. Jalan memiliki tipe dan karaketeristik sehingga perlu dilihat kondisi pada ruas jalan.
Rumambi, Ramon Charles   +2 more
core  

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

open access: yesAdvanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu   +10 more
wiley   +1 more source

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