Results 101 to 110 of about 4,899,194 (294)

Genome‐Wide and Multi‐Omics Analysis Identified DNA‐Interacting Circular RNA circFOXK2 as MLL1 Regulator for Histone H3K4 Methylation in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Circular RNA circFOXK2 is frequently upregulated in pancreatic ductal adenocarcinoma to promote tumor heterogeneity, growth, and metastasis. Through circRNA‐DNA interaction at different genomic locations, circFOXK2 removes the PPIE inhibitory effects on MLL1 for gene‐activating H3K4 methylation of the oncogenes.
Chi Hin Wong, Jessica Jazmin Peña‐Paladines, Sum Yin Valerie Leung, Ka‐Fai To, Kenneth Siu Ho Chok, Yangchao Chen   +5 more
wiley   +1 more source

Analysis of pulse propagation in a bottom limited sound channel with a surface duct

, 1993
An acoustic data set, that was collected in a bottom limited sound channel with a surface duct, has been modeled using broadband ray , normal mode , fast-field, and parabolic approximation techniques.
Monjo, Charles
core   +3 more sources

Surface morphology of the endolymphatic duct in the rat. A scanning electron microscopy study

, 1995
Following intracardiac vascular perfusion fixation of 8 rats with glutaraldehyde in a buffered and oxygenated blood substitute, the vestibular aqueduct and endolymphatic duct were opened by microsurgery of the resulting 16 temporal bones.
Bretlau, P, Qvortrup, K, Rostgaard, Jørgen   +2 more
core   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

4D fabrication of scaffolds facilitates the construction of cholangiocyte monolayers from human and mouse liver derived organoids

Materials Today Bio
The blockage and absence of bile ducts lead to liver defects, highlighting the urgent need for effective regenerative solutions. Tissue engineering has emerged as an interdisciplinary solution for repairing and regenerating damaged bile duct tissue ...
Junzhi Li, Shangsi Chen, Jing Chu, Yanghonghong Fei, Patrick Ho-Yu Chung, Kenneth Kak Yuen Wong, Vincent Chi Hang Lui, Paul Kwong Hang Tam   +7 more
doaj   +1 more source

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

Advanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang, Shijie He, Yuheng Chang, Sheng Mao, Jianan Canal Li, Binbin Chen, Hongxun Gao, Mingchun Xu, Chenxu Liu, Yajie Wang   +9 more
wiley   +1 more source

Estimates of the coherent leakage of sound from an ocean surface duct

, 2016
For underwater sound transmission in a mixed-layer surface duct, the trapping of sound and the coherent leakage of some of this energy from the duct are well known phenomena.
Adrian Jones (23437576), Z. Zhang (551978), Alec Duncan (23311570)   +2 more
core   +1 more source

The CXCL5/CXCR2 Axis Attenuates Ferroptosis in Intrahepatic Cholangiocarcinoma Through the Positive Feedback Loop Between PTGS2 Transcriptional Activation and Neutrophil Recruitment

Advanced Science, EarlyView.
The CXCL5/CXCR2 axis directly inhibits ferroptosis in ICC cells by activating the NF‐κB/PTGS2 pathway. Meanwhile, the CXCL5/CXCR2 axis recruits N2 TANs, and the activated PTGS2 promotes the secretion of TNF‐α from the recruited N2 TANs via the CCL2/CCL7/CCR2 pathway, thereby activating the NF‐κB/PTGS2 axis and forming a positive feedback loop, which ...
Chanqi Ye, Kefeng Lin, Shuyao Yang, Yan Zhang, Wenli Gao, Jiaqi Chen, Ying Dong, Rui Bai, Yang Tian, Minghao Wang, Zhijun Yuan, Yuxiao Ma, Yuqin He, Ruyin Chen, Wenguang Fu, Qi Jiang, Qiong Li, Jian Ruan   +17 more
wiley   +1 more source

Impact of Mesoscale Eddies on Acoustic Propagation Under a Rough Sea Surface

Remote Sensing
This study investigates the combined effects of mesoscale eddies and rough sea surfaces on acoustic propagation in the eastern Arabian Sea and Gulf of Aden during summer monsoon conditions.
Shaoze Zhang, Jian Shi, Xuhui Cao
doaj   +1 more source

Study on the key structure parameters of a gravity settling chamber based on a flow field simulation

Engineering Applications of Computational Fluid Mechanics, 2019
A gravity settling chamber plays an important role in improving the effect of the dust removal when it is selected as a dust collector in a pneumatic cleaning system for cleaning a subway tunnel. The settling rate and the indexes evaluating the secondary
Xiaojing Liu, Yicheng Zhang, Qiangyun Wu, Mingfeng Zhang, Fan Liu, Yuanchang Guo   +5 more
doaj   +1 more source