Results 141 to 150 of about 50,696 (309)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

A knowledge-based intelligent system for surface texture (virtual surf)

open access: yes
The presented thesis documents the investigation and development of the mathematical foundations for a novel knowledge-based system for surface texture (VitualSurf system). This is the first time that this type of novel knowledge-based system has been
Wang, Yan
core  

Effect of Some Cutting Parameters on Surface Finish of Bright Mild Steel

open access: yesJournal of Applied Sciences and Environmental Management
The objective of this paper was to evaluate the effect of some cutting parameters on surface finish of bright mild steel (BMS). Samples were cut into the required piece with dimension 50mm x 200mm and the turning operation done using a tungsten carbide ...
E. Obojoh, T. I. Francis-Akilaki
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Algorithms for Surface Texture Profiles and Parameters

open access: yes
This thesis is concerned with the development of algorithms for the reliable calculation of surface texture profile parameters published by the International Organisation for Standardisation (ISO).
Brennan, James K.
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Manufacturing surface technology : surface integrity & functional performance /

open access: yes, 2001
The first title in the "Manufacturing Engineering Modular" series, the publication of this book marks recognition of the effect of surface finish obtained in manufacture ("surface integrity") on the functional performance of product, in terms of such ...
Griffiths, Brian.
core  

Surface Finish Applications of Neural Networks

open access: yesMeasurement + Control, 2001
T S Sihra   +2 more
doaj   +1 more source

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