Results 161 to 170 of about 7,544,346 (399)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Effect of longitudinal surface finish on elastohydrodynamic lubrication [PDF]

open access: yes
The effect of longitudinal-lay surface finish on the elastohydrodynamic film thickness and the percentage of film between rolling disks in contact were evaluated using a rolling disk apparatus.
Dow, T. A., Kannel, J. W., Parker, R. J.
core   +1 more source

Surface Finish Applications of Neural Networks

open access: yesMeasurement + Control, 2001
T S Sihra   +2 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Material removal investigation in bonnet polishing of CoCr alloy [PDF]

open access: yes, 2012
The manufacture of orthopaedic joint bearings surfaces requires exceptionally high levels of control of not only the surface finish but also the surface form.
Blunt, Liam, Jiang, Xiang, Zeng, S.
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Dry sliding friction and wear response of WC-Co hardmetal pairs in linearly reciprocating and rotating contact [PDF]

open access: yes, 2011
This paper presents an experimental evaluation of friction and wear properties of WC-Co cemented carbides. A comparison is made between unlubricated rotating and linearly reciprocating pin-onplate sliding pairs. The plate specimens were WC-10wt%Co grades
Bonny, Koenraad   +7 more
core   +1 more source

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