Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Effect of aluminium sheet surface conditions on feasibility and quality of resistance spot welding [PDF]
A study investigating the effect of sheet surface condition on resistance spot welding (RSW) of aluminium has been carried out. This concentrates on two automotive aluminium alloys; AA5754 and AA6111, used for structural and closure applications ...
Briskham +14 more
core +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Computation of irradiance in a solar still by using a refined algorithm [PDF]
A refined solar algorithm from the ESP-r system has been used to calculate the distribution of solar irradiation inside a basin-type solar still. In the approach, surface finish, view factors and multiple reflections are taken into consideration in the ...
Clarke, Joseph Andrew, Madhlopa, Amos
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The application of Taguchi approach to optimise the processing conditions on bonnet polishing of CoCr [PDF]
This paper applied the Taguchi approach to investigate the effects of each polishing parameter and obtain the optimal processing conditions for CoCr alloy polishing.
Blunt, Liam, Jiang, Xiang, Zeng, Shengye
core +1 more source
Surface Finish Effects Using Coating Method on 3D Printing (FDM) Parts
One of three-dimensional (3-D) printing economical processes is by using Fused Deposition Modelling (FDM). The 3-D printed object was built using layer-by-layer approach which caused “stair stepping” effects. This situation leads to uneven surface finish
A. Haidiezul, AF Aiman, B. Bakar
semanticscholar +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The effect of rotor blade thickness and surface finish on the performance of a small axial flow turbine [PDF]
An experimental investigation was conducted to determine the effect of blade profile inaccuracies and surface finish on the aerodynamic performance of a 11.13 cm tip diameter turbine.
Haas, J. E., Roelke, R. J.
core +1 more source

