Results 81 to 90 of about 50,696 (309)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Enhancing the surface finish of single point diamond turning

open access: yes, 2011
Ultra precision single point diamond turning (SPDT) is a machining process used to produce optical grade surfaces in a wide range of materials. Aluminum is of primary interest as a workpiece material because it is easily diamond turnable, highly ...
Tauhiduzzaman, Mohammed
core  

The Effect of Finish-Milling Operation on Surface Quality and Wear Resistance of Inconel 625 Produced by Selective Laser Melting Additive Manufacturing

open access: yes, 2020
Additive Manufacturing (AM) has been recognized as a promising manufacturing technology for the industries including aerospace and biomedical; however, the surface finish requirement for the components used in such industries imposes a severe constraint.
KAYNAK, YUSUF
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Development of Regression Equation for Surface Finish and Analysis of Surface Integrity in EDM

open access: yes, 2013
Electrical discharge machining (EDM) is a relatively modern machining process having distinct advantages over other machining processes and can machine Ti-alloys effectively.
M. M., Rahman, Khan, Md. Ashikur Rahman
core  

Surface finish analysis of composite automotive panels [PDF]

open access: yes, 2007
Composite plates and panels are increasingly used in automotive body parts. These composite structures possess excellent strength and stiffness properties.
Hu, Shilian
core  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Rolling contact fatigue performance of HIPed Si3N4 with different surface roughness

open access: yes, 2001
Accelerated rolling contact fatigue four-ball tests were performed on hot isostatically pressed (HIPed) silicon nitride/steel contacts under lubricated condition using a PLINT TE92/HS microprocessor controlled rotary tribometer at a maximum compressive ...
Kang, J   +5 more
core   +1 more source

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