Results 31 to 40 of about 159,531 (259)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Effects of surface charge and boundary slip on time-periodic pressure-driven flow and electrokinetic energy conversion in a nanotube

Beilstein Journal of Nanotechnology, 2019
Time-periodic pressure-driven slip flow and electrokinetic energy conversion efficiency in a nanotube are studied analytically. The slip length depends on the surface charge density.
Mandula Buren, Yongjun Jian, Yingchun Zhao, Long Chang, Quansheng Liu   +4 more
doaj   +1 more source

On the scaling of the slip velocity in turbulent flows over superhydrophobic surfaces [PDF]

Physics of Fluids, 2016
Superhydrophobic surfaces can significantly reduce hydrodynamic skin drag by accommodating large slip velocity near the surface due to entrapment of air bubbles within their micro-scale roughness elements. While there are many Stokes flow solutions for flows near superhydrophobic surfaces that describe the relation between effective slip length and ...
Jongmin Seo, Ali Mani
openaire   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Wind Stress Effects on Drone‐Based Thermal Infrared Surface Velocimetry Measurements of Tidal Flow in an Estuary

Water Resources Research
We evaluate the effect of surface wind stress on remote velocimetry measurements of tidal flow by comparing these measurements to the bulk flow velocity measured by a co‐located acoustic velocity profiler in a tidal channel.
Evan T. Heberlein, Marc Mayes, Bryn E. Morgan, Kelly K. Caylor, Seth A. Schweitzer, Edwin A. Cowen   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Optimization of the gas flow system in a selective laser melting chamber using numerical methods

Advances in Mechanical Engineering
A well-designed flow field is a key factor to improve the surface quality of products by removing spatter, which is often generated during the selective laser melting (SLM) process.
Zirong Zhou, Yongxing Li, Xiaoxuan Chen, Xin Shang, Kunzheng Gou, Lijuan Pang   +5 more
doaj   +1 more source

Assisting and opposing flow of a MHD hybrid nanofluid flow past a permeable moving surface with heat source/sink and thermal radiation

Partial Differential Equations in Applied Mathematics, 2021
The aim of the current investigation is to study the assisting and opposing flow effects on hybrid nanofluid (SiO2-MoS2/water) flow past a moving surface under the impact of heat source/sink, thermal radiation and velocity slip.
Moh Yaseen, Manoj Kumar, Sawan Kumar Rawat   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source