Results 61 to 70 of about 198,581 (309)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Channel flow over large cube roughness: a direct numerical simulation study [PDF]

, 2010
Computations of channel flow with rough walls comprising staggered arrays of cubes having various plan area densities are presented and discussed. The cube height h is12.5% of the channel half-depth and Reynolds numbers (u? h/?) are typically around 700 –
IAN P. CASTRO, Leonardi, Stefano, STEFANO LEONARDI, Castro, Ian P.   +3 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Investigation of Flow Parameters for Titanium Cold Spraying using CFD Simulation [PDF]

, 2010
A comprehensive study of cold gas dynamic spray technology is required for optimising performance and gun design for spraying various materials. Cold spraying technology is a new technique in industry and very limited data is available.
Singh, Tejinder
core  

Study of a laminar falling film flowing over a wavy wall column: Part I. Numerical investigation of the flow pattern and the coupled heat and mass transfer [PDF]

, 2001
Flow pattern and heat and mass transfer characteristics for a film flowing over a vertical wavy column are numerically investigated in a laminar flow regime.
Prevost, Michel, Negny, Stéphane, S Negny, M Prevost, Meyer, Michel, M Meyer   +5 more
core   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Simulation of rough wall turbulent channel flow using a parametric forcing approach [PDF]

, 2011
The effects of rough walls on turbulent channel flow are simulated by adding a simple forcing term to the Navier-Stokes equations. An extensive parameter study is used to explore the effects of this term on turbulent channel flow.
Busse, A., Busse, A.E., Sandham, N.D.
core   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Airborne radar evidence for tributary flow switching in Institute Ice Stream, West Antarctica: implications for ice sheet configuration and dynamics [PDF]

, 2015
Despite the importance of ice streaming to the evaluation of West Antarctic Ice Sheet (WAIS) stability we know little about mid- to long-term dynamic changes within the Institute Ice Stream (IIS) catchment.
Martin J. Siegert, Hugh F. J. Corr, Corr, Hugh, Bingham, RG, Woodward, John, Ross, Neil, Ross, N, Dunning, SA, Corr, Hugh F.J., Winter, K, Siegert, MJ, Robert G. Bingham, Winter, Kate, Dunning, Stuart, John Woodward, Neil Ross, Siegert, Martin, Corr, HFJ, Kate Winter, Dunning, Stuart A., Siegert, Martin J., Stuart A. Dunning, Bingham, Robert G., Woodward, J   +23 more
core   +1 more source