Results 121 to 130 of about 198,686 (307)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Effects of surface hardening by laser shock peening and shot peening on a nickel-based single-crystal superalloy CMSX-4

Materials Research Express
Improving the expected life of nickel-based single-crystal superalloy turbine components by surface hardening treatments including laser shock peening (LSP) and mechanical shot peening (MSP) are of particular interest for mitigation of life limiting ...
Aabid Husen Hakeem, Nicolau I Morar, Karl Dawson, Gordon J Tatlock, Grant J Gibson, Simon Gray   +5 more
doaj   +1 more source

A Study on Surface Hardening and Wear Resistance of AISI 52100 Steel by Ultrasonic Nanocrystal Surface Modification and Electrolytic Plasma Surface Modification Technologies. [PDF]

Materials (Basel), 2023
Magazov N, Satbaeva Z, Rakhadilov B, Amanov A.   +3 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Combining the Finite Element Analysis and Kriging Model for Study on Laser Surface Hardening Parameters of Pitch Bearing Raceway. [PDF]

Materials (Basel), 2022
Zhang H, Zhu M, Ji S, Dou Y.
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Effect of Surface Hardening on Dynamic Frictional Rolling Contact Behavior and Degradation of Corrugated Rail

Shock and Vibration, 2019
The present study was undertaken to evaluate the effect of surface hardening technology on dynamic frictional rolling contact behavior and degradation of corrugated rail in Shenzhen.
Yuan Gao, Jingmang Xu, Ping Wang, Yibin Liu   +3 more
doaj   +1 more source

An adaptive finite element method for laser surface hardening of steel problem [PDF]

, 2011
ACMAC’s PrePrint Repository aim is to enable open access to the scholarly output of ...
Gupta Nupur, Nataraj Neela, Neela Nataraj, Nupur Gupta   +3 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Surface work-hardening optimization of cold roll-beating splines based on an improved double-response surface-satisfaction function method

Advances in Mechanical Engineering, 2018
The work hardening of a spline during cold roll-beating is used as an indicator to evaluate the mechanical properties of the surface. To further optimize the work-hardening degree of a cold roll-beating spline surface, weight theory and satisfaction ...
Fengkui Cui, Yongxiang Su, Xiaoqiang Wang, Xiang Yu, Xiaolin Ruan, Libo Liu   +5 more
doaj   +1 more source