Results 151 to 160 of about 4,514,829 (351)
Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle
Advanced Functional Materials, EarlyView.This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang +18 more
wiley +1 more source
Report of the Workshop on the Significance of Changes in Surface CO2 and Ocean pH in ICES Shelf Sea Ecosystems (WKCpH) [2–4 May 2007 London, UK] [PDF]
, 2007 Contributors: Knut ...
ICES
core
Advanced Functional Materials, EarlyView.An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal +21 more
wiley +1 more source
Topographic Relaxation of Complex Impact Craters in a Clathrate Crust on Titan
The Planetary Science JournalTitan’s impact craters are significantly shallower than fresh craters on Ganymede, which are often used as templates for fresh craters on Titan. The presence of a clathrate crust on Titan, which would insulate the ice shell and maintain warmer ice near ...
Gwendolyn Brouwer +5 more
doaj +1 more source
Snow–Ice Morphological Relationship under Sea Ice Surface Topographic Control: Evidence from In Situ RTK Measurements [PDF]
Mingfeng Wang, Jie Su, Hao Li, Tao Li
openalex +1 more source
Report of the ICES/EuroGOOS Planning Group for the North Sea Pilot Project (PGNSP) [8-9 May 2006 ICES Headquarters, Denmark] [PDF]
, 2006 Contributors: Hein Rune Skjoldal, Henrik Søiland and Else ...
ICES
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Advanced Functional Materials, EarlyView.Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou +6 more
wiley +1 more source
Rapid Impact Crater Relaxation Caused by an Insulating Methane Clathrate Crust on Titan
The Planetary Science JournalTitan’s impact craters are hundreds of meters shallower than expected, compared to similar-sized craters on Ganymede. Only 90 crater candidates have been identified, the majority of which have low certainty of an impact origin.
Lauren R. Schurmeier +5 more
doaj +1 more source
Genetically Programmed Shape‐Morphing of Engineered Living Materials
Advanced Functional Materials, EarlyView.Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker +7 more
wiley +1 more source