Results 111 to 120 of about 144,391 (309)
Surface-impedance engineering for advanced wave transformations
, 2020 The public defense on 29th May 2020 at 18:00 (6 p.m.) will be organized via remote technology. Link: https://aalto.zoom.us/j/65114599050 Zoom Quick Guide: https://www.aalto.fi/en/services/zoom-quick-guideMetasurfaces are ultrathin artificial material ...
Wang, Xuchen
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Sound radiation from perforated plates [PDF]
, 2008 Perforated plates are quite often used as a means of engineering noise control to reduce the sound radiated by structures. However, there appears to be a lack of representative models to determine the sound radiation from a perforated plate.
Putra, Azma
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Electrochemical Impedance Imaging on Conductive Surface
, 2022 Electrochemical impedance spectroscopy (EIS) is a powerful tool to measure and quantify the system impedance. It allows to characterize the electrocatalytic and battery reactions.
Shi, Yaping
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Towards spatially resolved impedance analysis of adherent cells
, 2022 S.73Commercial impedance sensing systems nowadays contain only one electrode or a connected set of electrodes per well. For some applications it would be of great interest to measure the impedance spectrum of areas of a cell culture separately, e.g.
Schächtele, Jonathan, Stein, Johannes
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source