Results 81 to 90 of about 5,203,929 (306)

Numerical study on instability characteristics and influencing factors of inclined rock–coal–rock composite structures

Energy Exploration & Exploitation
Failure and instability of inclined rock–coal–rock composite structures (IRCRS) are critical contributing factors to impact-induced mining disasters, particularly in scoured coal seams.
Xiaozhen Chen, Heng Zhang, Yawei Zhu, Xiangqian Chen, Feifei Yang, Xiaokang Sun, Xi Chen   +6 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Experimental study on the mechanical properties and crack evolution patterns of sandstone with prefabricated double fractures in sub-instability stage

矿业科学学报
As coal mining in China gradually shifts from shallow to deep layers, the impact of mining disturbances increases, making it more difficult to control the development of surrounding rock fractures. This study aims to investigate the effect of rock bridge
CUI Yi, PU Yuanyuan, CHEN Ziyang, MENGLI Deren, CHEN Jie   +4 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Mesoscale subduction at the Almeria-Oran front. Part 1: ageostrophic flow [PDF]

, 2001
This paper presents a detailed diagnostic analysis of hydrographic and current meter data from three, rapidly repeated, fine-scale surveys of the Almeria-Oran front.
Ruiz, S., Tintore, J., Allen, J.T., J. Tintoré, Smeed, David, D. A. Smeed, S. Ruiz, Ruiz, Simón, Tintoré, Joaquín, Allen, John T., Smeed, D.A., J. T. Allen   +11 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Three-dimensional flow instability in a lid-driven isosceles triangular cavity [PDF]

, 2011
Linear three-dimensional modal instability of steady laminar two-dimensional states developing in a lid-driven cavity of isosceles triangular cross-section is investigated theoretically and experimentally for the case in which the equal sides form a ...
J. KÜHNEN, Kuhlmann, Hendrik, Theofilis, Vassilios, Kuhlmann, H. C., H. C. KUHLMANN, Gonzales, Leo M., M. AHMED, González Gutierrez, Leo Miguel, Kühnen, Jakob, Ahmed, Manzoor, V. THEOFILIS, L. M. GONZÁLEZ, Kuhnen, J.   +12 more
core   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Finite size effects near the onset of the oscillatory instability [PDF]

, 1996
A system of two complex Ginzburg - Landau equations is considered that applies at the onset of the oscillatory instability in spatial domains whose size is large (but finite) in one direction; the dependent variables are the slowly modulated complex ...
Martel, Carlos, Vega de Prada, José Manuel   +1 more
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source