Results 91 to 100 of about 1,351,422 (353)
Mechanical strength of ground WC-Co cemented carbides after coating deposition [PDF]
Manufacturing of hardmetal tools often involves surface grinding, ion etching and final coating. Each stage throughout the manufacturing chain introduces surface integrity changes which may be critical for defining the final mechanical behavior of the ...
Esteve Pujol, Joan +4 more
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Surface integrity parameters such as surface topography, hardness gradient, and residual stress have significant impacts on contact fatigue of tooth surface.
Yuqin Wen, Wei Zhou, Jinyuan Tang
doaj +1 more source
Optimization of hot press forging parameters in direct recycling of aluminium chip (AA 6061) [PDF]
This study introduces a new approach of direct recycling using the hot press forging process that eliminates the two intermediate processes of cold-compact and pre-heating. This method leads to low energy consumption without intervening the metallurgical
Ahmed, Rizwan +5 more
core +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Integrable Curves and Surfaces
The surfaces in three dimensional Euclidean space ${\mathbb R}^3$ obtained through the use of the soliton techniques are called integrable surfaces. Integrable equations and their Lax equations possess certain symmetries. Infinitesimal versions of these symmetries are deformations which are responsible in constructing the integrable surfaces. There are
Gurses, Metin, Tek, Suleyman
openaire +3 more sources
Factors Affecting Plunge Grinding Force [PDF]
Grinding force has a close relation to grinding inputs such as grinding wheel, work material, interference condition, grinding speed, grinding fluid and machine condition, and therefore varies widely with grinding inputs.
Nakajima, Toshikatsu, Uno, Yoshiyuki
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The influence of surface treatment of PVD coating on its quality and wear resistant [PDF]
The article deals with a determination of the influence of a cutting edge preparation on the quality and wear resistance of coated cutting tools. Cutting inserts made from a sintered carbide with a deposited layer of PVD coating were selected for ...
Malotová, Šárka +3 more
core +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

