Results 101 to 110 of about 1,351,422 (353)
Assessment of casting filling by modeling surface entrainment events using CFD [PDF]
, 2010 The reliability of cast components is dependent on the quality of the casting process. During this highly transient filling phase the prevention of free surface turbulence and consequential oxide entrainment is critical to ensure the mechanical integrity
Gebelin, J. C. +3 more
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Identification of influent factors on surface integrity in nickel-base superalloy drilling [PDF]
, 2010 For the critical rotating components in aeronautical industry, the metallurgical quality achieved after machining conditions could determine their mechanical behaviour in fatigue. To guarantee this quality, the tools, materials and cutting conditions are
Baili, Maher +4 more
core +1 more source
An assessment of blockchain consensus protocols for the Internet of Things [PDF]
, 2018 In a few short years the Internet of Things has become an intrinsic part of everyday life, with connected devices included in products created for homes, cars and even medical equipment.
Bellekens, Xavier +2 more
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
An analysis of surface integrity when drilling inconel 718 using palm oil and synthetic ester under, MQL condition [PDF]
, 2011 The components being manufactured in the aerospace industry must be capable of being utilized for long periods without failure. Thus, the functional behavior of these machined components is greatly dependent upon their surface integrity. The present work
A. Rahim, Erween, Sasahara, Hiroyuki
core
Observation of Bloch-point domain walls in cylindrical magnetic nanowires
, 2013 Topological protection is an elegant way of warranting the integrity of quantum and nanosized systems. In magnetism one example is the Bloch-point, a peculiar object implying the local vanishing of magnetization within a ferromagnet.
Afid, Raja +10 more
core +3 more sources
Endothelial glycocalyx: Role in body fluid homeostasis and fluid management [PDF]
, 2019 Endothelial glycocalyx layer (EGL) coating the luminal surface of vascular endothelium plays an essential role in maintaining the normal fluid homeostasis of the body.
Goswami, Shreya, Kundra, Pankaj
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Surface integrity analysis when milling ultrafine-grained steels
Materials Research, 2012 This paper quantifies the effects of milling conditions on surface integrity of ultrafine-grained steels. Cutting speed, feed rate and depth of cut were related to microhardness and microstructure of the workpiece beneath machined surface.
Alessandro Roger Rodrigues +7 more
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