Results 91 to 100 of about 842,358 (313)
, 2023 Improving the performance of blood-contacting medical implants is a global health necessity aimed at reducing mortality and morbidity in patients with cardiovascular diseases.
Tohid, Didar +2 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Frontiers in MedicineIntroductionMyopia is a multifactorial condition driven by an interplay of genetic predisposition and environmental triggers. This study aims to harmonize and analyze risk predictors from two distinct datasetsone historical and clinical, the other ...
Jiajia Liao, Zhijie Chen, Wanqing Jin
doaj +1 more source
The influence of the surface morphology of dental implants on bone integration
Fogorvosi Szemle, 2019 Surface morphology of dental implants is one of the Bränemark osseointegration conditions formulated in the eighties. In the past couple of decades – as in many other areas within oral implantology – significant changes have taken place.
Ferenc Koppány
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
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Next MaterialsThe deposition of Ni-P on the surface of ceramic powders by the electroless method holds significant potential for enhancing the mechanical properties of the coating.
Peng Tang +3 more
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Characterization and chemical modification of the silica surface /
, 1995 Oxide surface materials are widely used in many applications, in particular where chemically modified oxide surfaces are involved. Indeed, in disciplines such as separation, catalysis, bioengineering, electronics, ceramics, etc., modified oxide surfaces ...
Voort, P. van der(Pascal) +2 more
core
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
, 2023 To improve the fatigue life of the key component and the surface properties of the 30CrNi2MoVA steel material, advanced ultrasonic-milling composite superficial treatment was performed. The microstructure, surface roughness, friction and wear performance,
Dan Liu +6 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source