Results 161 to 170 of about 1,991,182 (287)

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Improved adhesion and function of Pediococcus pentosaceus Li05 for acute colitis through surface modification. [PDF]

NPJ Sci Food
Han S, Wang K, Su K, Dong X, Huang Y, Lu Y, Zhang S, Qiu B, Li Y, Xiao H, McClements D, Berglund B, Yao M, Li L.   +13 more
europepmc   +1 more source

Surface Modification Technologies

, 2016
The present work has been conducted in order to assess the mechanical and tribological performance of a ZrN coating deposited onto a H13 steel substrate by means of a closed field unbalanced magnetron-sputtering ion-plating (CFUMSIP) process. The hardness and elastic modulus of the coated system have been determined by means of nanoindentation ...
STAIA, Mariana, TROCELIS, A, ZAIRI, Amel, SUAREZ, M, PUCHI-CABRERA, Eli-Saul, IOST, Alain, MONTAGNE, Alex   +6 more
openaire   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Magnetoplasmonic Nanostructures from Magnetite with Noble Metal Surface Modification and Their Antimicrobial Activity. [PDF]

Int J Mol Sci
Ardeleanu H, Ardeleanu MC, Dunca S, Grigoras M, Ababei G, Pricop D, Ursu L, Bulai G, Timpu D, Lupu N, Ciobica A, Racuciu M, Creanga D.   +12 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Cationic Surface Modification Combined with Collagen Enhances the Stability and Delivery of Magnetosomes for Tumor Hyperthermia. [PDF]

J Funct Biomater
Wang Y, Lin C, Zhang Y, Li W, Cui H, Li B, Liu Z, Wang K, Wang Q, Wang Y, Lv K, Huang Y, Zhuang H, Qin S.   +13 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Engineering bacteria for enhanced tumor therapy: from surface modification to synthetic genetic circuits. [PDF]

J Hematol Oncol
Wang Y, Xiao S, Yu W, Han B, Guo G.
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source