Results 51 to 60 of about 839,368 (266)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Morphology of two-dimensional fracture surfaces [PDF]

Journal of Statistical Mechanics: Theory and Experiment, 2006
slightly ...
Alava, Mikko J., Nukala, Phani K. V. V., Zapperi, Stefano   +2 more
openaire   +4 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Stable isotope ecology of Quaternary cervid and bovid species in Southeast Asia with implications for wildlife conservation

Scientific Reports
Southeast Asia, one of the major biodiversity hotspots, is experiencing substantial species loss, with predictions indicating that 13–85% of species are threatened to lose their original habitats.
Sanah Shaikh, Hervé Bocherens, Kantapon Suraprasit   +2 more
doaj   +1 more source

The grinding surface characteristics and evaluation of particle-reinforced aluminum silicon carbide

Science and Engineering of Composite Materials, 2016
The changes in grinding parameters have direct influences on the characteristics of surface morphology of workpieces during grinding. On the basis of the application of particle-reinforced aluminum silicon carbide (SiCp/Al), this paper analyzes the ...
Liang Guiqiang, Zhou Xiaoqin, Zhao Feifei   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Numerical and Experimental Investigation of Bonding Evolution of Bi-Metal Al/Br Laminates Fabricated Via Asymmetric Roll Bonding

Acta Technologica Agriculturae, 2023
Materials and alloys usually possess distinct properties. In contrast to conventional materials, employment of bi-metal laminates allows achievement of better performance in various properties, such as light density, high strength, high corrosion and ...
Abd Gufran, Jalil Abduladheem Turki, Patra Indrajit, Izzat Samar Emad, Dwijendra Ngakan Ketut Acwin, Aravindhan Surendar, Vini Mohamad Heydari, Daneshmand Saeed   +7 more
doaj   +1 more source

SURFACE MORPHOLOGY OF GaN SURFACES DURING MOLECULAR BEAM EPITAXY [PDF]

Surface Review and Letters, 2000
The reconstruction and surface morphology of gallium nitride (0001) and [Formula: see text] surfaces are studied using scanning probe microscopy and reflection high energy electron diffraction. Results for bare GaN surfaces are summarized, and changes in the surface structure and morphology due to codeposition of indium or magnesium during growth are ...
Feenstra, R., Chen, H., Ramachandran, V., Lee, C., Smith, A., Northrup, J., Zywietz, T., Neugebauer, J., Greve, D.   +8 more
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source