Results 41 to 50 of about 793,915 (265)

Topological evolution of surface transportation networks [PDF]

Computers, Environment and Urban Systems, 2009
This study explores the topological evolution of surface transportation networks, using empirical evidence and a simulation model validated on that data. Evolution is an iterative process of interaction, investment, and disinvestment. The temporal change of topological attributes for the network is also evaluated using measures of connectivity, density,
Feng Xie, David Levinson
openaire   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Regional Cooperation for Climate Mitigation: Potential to Slow Future Warming in South Asia

Ecosystem Health and Sustainability
This study examines historical trends and future projections of extreme temperature indices in Bangladesh–India–Myanmar (BIM), a region of critical importance for regional food security and socioeconomic stability.
Xinyi Fan, Junbang Wang, Zhixin Hao, Xiaofang Sun, Meng Wang, Shaoqiang Wang   +5 more
doaj   +1 more source

Intelligent reflecting surface‐aided network planning

IET Communications, 2022
Intelligent reflecting surface (IRS) composed of a large number of low‐cost, phase‐adjustable passive reflecting elements, which is an attractive solution of overcoming the signal attenuation and interference.
Fan‐Hsun Tseng, Yu‐Shan Liang, Yen‐Wu Ti, Chia‐Mu Yu   +3 more
doaj   +1 more source

Using the dynamics of productivity and precipitation-use efficiency to detect state transitions in Eurasian grasslands

Frontiers in Ecology and Evolution, 2023
In the face of accelerated global dryland expansion and grassland degradation, signaling grassland ecosystem state transitions is an ongoing challenge in ecology.
Tianyou Zhang, Zhi Chen, Zhi Chen, Zhi Chen, Cuicui Jiao, Weikang Zhang, Lang Han, Zheng Fu, Zhongyi Sun, Zhaogang Liu, Zhaogang Liu, Zhongming Wen, Guirui Yu, Guirui Yu, Guirui Yu   +14 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A Lightweight Sea Surface Object Detection Network for Unmanned Surface Vehicles

Journal of Marine Science and Engineering, 2022
For unmanned surface vehicles (USVs), perception and control are commonly performed in embedded devices with limited computing power. Sea surface object detection can provide sufficient information for USVs, while most algorithms have poor real-time ...
Zhangqi Yang, Ye Li, Bo Wang, Shuoshuo Ding, Peng Jiang   +4 more
doaj   +1 more source

Networks from drug–drug surfaces

Molecular Systems Biology, 2007
Mol Syst Biol. 3: 85 Multi‐drug combinations are vital in modern medicine (Keith et al , 2005; Fitzgerald et al , 2006). Such drug combinations can also be used to probe the relationships between proteins in a network, and progress towards using drug interactions to infer network connectivity has been made in recent years.
Yeh, Pamela, Kishony, Roy
openaire   +4 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source