Results 51 to 60 of about 793,915 (265)

Bioconversion of Alternative Substrates for the Biosynthesis of HMG-CoA Reductase Inhibitors by Aspergillus spp. Strains with Antimicrobial Potential

Fermentation
Simvastatin, a semisynthetic drug widely used to lower cholesterol, is among the most prescribed statins worldwide. This study focuses on the direct production of a simvastatin-like biomolecule using alternative substrates by Aspergillus spp.
Uiara M. de B. L. Lins, Rafael de S. Mendonça, Sérgio S. S. Dantas, Adriana Ferreira de Souza, Dayana Montero-Rodríguez, Rosileide F. da S. Andrade, Galba M. Campos-Takaki   +6 more
doaj   +1 more source

Biocompatibilidad de osteoblastos e inhibición de adhesión bacteriana a la aleación Ti6Al4V tratada térmica y químicamente

Revista de Metalurgia, 2021
El objetivo de este trabajo ha sido estudiar si los tratamientos térmicos y de conversión química mejoran la biocompatibilidad de la aleación TiAlV y reducen el crecimiento bacteriano.
Greta Tavarez-Martínez, Belén Criado, M. Coronada Fernández-Calderón, Edgar Onofre-Bustamante, Ciro Pérez-Giraldo, Cristina García-Alonso, Mª Lorenza Escudero   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Surface Coverage in Wireless Sensor Networks [PDF]

IEEE INFOCOM 2009, 2009
Coverage is a fundamental problem in Wireless Sensor Networks (WSNs). Existing studies on this topic focus on 2D ideal plane coverage and 3D full space coverage. The 3D surface of a targeted Field of Interest is complex in many real world applications; and yet, existing studies on coverage do not produce practical results.
Ming-Chen Zhao, Jiayin Lei, Min-You Wu, Yunhuai Liu, Wei Shu   +4 more
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Bioemulsifier Produced by Aspergillus niger UCP 1064 Isolated from Caatinga Soil as a Promising Molecule for Scaled-Up Pharmaceutical Applications

Fermentation
This study presents the production, characterization, and potential pharmaceutical application of a bioemulsifier synthesized by Aspergillus niger UCP 1064 by submerged fermentation using agro-industrial residues (cassava wastewater and soluble starch ...
Uiara Maria de Barros Lira Lins, Rosileide Fontenele da Silva Andrade, Galba Maria de Campos-Takaki   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Climate and anthropogenic activities control spatiotemporal dynamics of topsoil inorganic carbon in China

Communications Earth & Environment
Soil inorganic carbon (SIC) comprises nearly half of terrestrial carbon storage and is vital for climate regulation. While previous studies focused on SIC’s size, composition, and distribution, its temporal dynamics and drivers remain understudied. Here,
Qiongyu Zhang, Jianxing Zhu, Qiufeng Wang, Guirui Yu, Cong-Qiang Liu   +4 more
doaj   +1 more source

Soil erosion affects variations of soil organic carbon and soil respiration along a slope in Northeast China

Ecological Processes, 2019
Background Although soil erosion plays a key role in the carbon cycle, a holistic and mechanistic understanding of the soil erosion process within the cycle is still lacking. The aim of this study was therefore to improve our mechanistic understanding of
Tong Li, Haicheng Zhang, Xiaoyuan Wang, Shulan Cheng, Huajun Fang, Gang Liu, Wenping Yuan   +6 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source