Results 61 to 70 of about 793,915 (265)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Earth's Future, 2022 Atmospheric wet deposition has attracted much attention because of its removal function of aerosol particles and impact on ecosystem. It is a complex multi‐component process due to various pollutants emission sources and reaction processes.
Qiongyu Zhang +7 more
doaj +1 more source
In-network surface simplification for sensor fields [PDF]
Proceedings of the 13th annual ACM international workshop on Geographic information systems, 2005 Recent research literature on sensor network databases has focused on finding ways to perform in-network aggregation of sensor readings to reduce the message cost. However, with these techniques information about the state at a particular location is lost.
Brian Harrington 0001, Yan Huang 0002
openaire +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Patterns of soil respiration and its temperature sensitivity in grassland ecosystems across China [PDF]
Biogeosciences, 2018 Soil respiration (Rs), a key process in the terrestrial carbon cycle, is very sensitive to climate change. In this study, we synthesized 54 measurements of annual Rs and 171 estimates of Q10 value (the temperature sensitivity of soil respiration) in ...
J. Feng, J. Wang, Y. Song, B. Zhu
doaj +1 more source
Surface entanglement in quantum spin networks [PDF]
Physical Review A, 2013 8 pages, 8 ...
ZIPPILLI, STEFANO +2 more
openaire +3 more sources