Results 111 to 120 of about 1,188,516 (315)

Identification and characterization of two temperature-induced surface-associated proteins of Streptococcus suis with high homologies to members of the arginine deiminase system of Streptococcus pyogenes

open access: yes, 2002
The present study was performed to identify stress-induced putative virulence proteins of Streptococcus suis. For this, protein expression patterns of streptococci grown at 32, 37, and 42°C were compared by one- and two-dimensional gel electrophoresis ...
Gruening, P.   +6 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

On rational maps from a general surface in P^3 to surfaces of general type

open access: yes, 2008
We study dominant rational maps from a general surface in $\mathbb P^{3}$ to surfaces of general type. We prove restrictions on the target surfaces. We show that for small degree the general surface has no such map.
Lucio Guerra, PIROLA, GIAN PIETRO
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

On algebraic surfaces of general type with negative [PDF]

open access: yesCompositio Mathematica, 2016
We prove that for any prime number $p\geqslant 3$ , there exists a positive number $
openaire   +1 more source

Comparison of Stochastic Methods for the Variability Assessment of Technology Parameters [PDF]

open access: yes, 2011
This paper provides and compares two alternative solutions for the simulation of cables and interconnects with the inclusion of the effects of parameter uncertainties, namely the Polynomial Chaos (PC) method and the Response Surface Modeling (RSM).
Stievano, Igor Simone   +7 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

The role of the scale and the frequency bandwidth of steering wheel vibration on road surface recognition

open access: yes, 2006
Automobile drivers are regularly exposed to vibrational stimuli in their vehicle. Of the automobile subsystems, the steering wheel is one of the most important due to its role in controlling the vehicle.
Giacomin, J, Woo, Y J
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

The Belvedere Glacier elevation change between 1951 and 2023

open access: yesActa Universitatis Carolinae Geographica
This study describes and analyses elevation changes in the debris-covered tongue of the surge-type Belvedere Glacier (Western Italian Alps) between 1951 and 2023 using remote sensing data, including historical aerial photographs, Lidar and drone ...
Lukáš Brodský   +5 more
doaj   +1 more source

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