Results 51 to 60 of about 5,685,494 (281)

Characterization and Sensing of Inert Gases with a High-Resolution SPR Sensor

open access: yesSensors, 2020
It is generally difficult to characterize inert gases through chemical reactions due to their inert chemical properties. The phase interference-sensing system based on high-resolution surface plasmon resonance (SPR) has an excellent refractive index ...
Zhenchao Liu, Jinlong He, Sailing He
doaj   +1 more source

Microfluidics-Based Plasmonic Biosensing System Based on Patterned Plasmonic Nanostructure Arrays

open access: yesMicromachines, 2021
This review aims to summarize the recent advances and progress of plasmonic biosensors based on patterned plasmonic nanostructure arrays that are integrated with microfluidic chips for various biomedical detection applications.
Yanting Liu, Xuming Zhang
doaj   +1 more source

Metasurface‐Enabled Helical Wavefront Fingerprint Metrology for Quantitative Retrieval of Liquid Optical Constants

open access: yesAdvanced Science, EarlyView.
A metasurface‐enabled helical wavefront fingerprint (MHWF) paradigm is proposed for quantitative and specific retrieval of a liquid medium's refractive index and extinction coefficient. The liquid's complex dielectric response governs the wavefront evolution of the metasurface‐generated focused vortex beam, forming a distinctive three‐dimensional ...
Yuting Zhou   +10 more
wiley   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv   +16 more
wiley   +1 more source

Palladium on Plastic Substrates for Plasmonic Devices

open access: yesSensors, 2015
Innovative chips based on palladium thin films deposited on plastic substrates have been tested in the Kretschmann surface plasmon resonance (SPR) configuration.
Paola Zuppella   +8 more
doaj   +1 more source

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao   +12 more
wiley   +1 more source

Applications of Surface Plasmon Resonance (SPR) for the Characterization of Nanoparticles Developed for Biomedical Purposes [PDF]

open access: yesSensors, 2012
Great interest is currently being devoted to the development of nanoparticles (NPs) for biomedical purposes, designed to improve the pharmacokinetic profile of their cargos (either imaging probes or drugs) and to enhance the specific targeting at the disease site.
Mara Canovi   +7 more
openaire   +5 more sources

A New Recruitable E3 Ligase UHRF1 Supporting Targeted Protein Degradation: A Minimal Azide as a Recruitment Ligand

open access: yesAdvanced Science, EarlyView.
Targeted protein degradation is often limited by the scarcity of usable E3 ligases. Herein, we report the first small‐molecule GPX4 degraders that incorporate either electrophilic warheads or a minimal azide group as an E3 recruitment ligand. The azide‐based degrader DK‐5070 effectively drives potent GPX4 degradation; mechanistic studies reveal that ...
Zehong Lin   +14 more
wiley   +1 more source

30 Years of Surface Plasmon Resonance (SPR) for Biosensing [PDF]

open access: yesPlasmonics, 2014
The year 2013 marked the 30th anniversary of the publication of a paper that changed the world of chemical and biomedical diagnostics: The manuscript of Bo Liedberg, Claes Nylander, and Ingemar Lundstrom entitled “Surface plasmon resonance for gas detection and biosensing” (Sensors and Actuators 4: 299) introduced the application of a physical concept,
openaire   +1 more source

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