Results 121 to 130 of about 15,565,904 (256)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

New ab initio potential energy surface and quantum dynamics of the reaction H(2S) + NH(X3Σ-) → N(4S) + H2

open access: yes, 2011
New ab initio potential energy surface and quantum dynamics of the reaction H(2S) + NH(X3Σ-) → N(4S ...
翟红生, 韩克利
core  

Plasma nitrided ferritic stainless steel surfaces as hydrogen permeation barriers [PDF]

open access: yes
Publisher Copyright: © 2025 The AuthorsHydrogen has the potential to replace fossil fuels in certain sectors where decarbonization presents significant challenges.
Astudillo Bautista, Milena Mishell   +1 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Measurement channels’ information relationships in body surface potential mapping

open access: yes
Body Surface Potential Mappings (BSPM) measurements allow heart rate monitoring. Based on measurements obtained from BSPM, defects and heart rhythm disorders can be detected.
Mariusz Sutryk   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

First-Principles Study Of Surface Phonons On The Aln(110) Surface

open access: yes, 2004
Using a linear-response approach based on the pseudo-potential method and the local density functional scheme, we have performed calculations of the atomic and dynamical properties of the (110) surface of the cubic phase of AlN.
Tütüncü, Hüseyin Murat   +5 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Role of Plasma Surface Treatments on Wetting and Adhesion

open access: yes, 2009
There are many current and emerging wetting and adhesion issues which require an additional surface processing to enhance interfacial surface properties.
Sparavigna, Amelia Carolina   +4 more
core   +1 more source

Effect of Composition and Surface Microstructure in Self-Polarized Ferroelectric Polymer Films on the Magnitude of the Surface Potential. [PDF]

open access: yesNanomaterials (Basel), 2023
Kochervinskii VV   +8 more
europepmc   +1 more source

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