Results 131 to 140 of about 4,267,348 (351)

Automotive Radar in a UAV to Assess Earth Surface Processes and Land Responses. [PDF]

open access: yesSensors (Basel), 2020
Weber C   +4 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Multiyear in-situ L-band microwave radiometry of land surface processes on the Tibetan Plateau. [PDF]

open access: yesSci Data, 2020
Su Z   +15 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Process, Causes, and Loss Assessment of the Extreme Wind-Dust Compound Disaster in China in April 2025

open access: yesInternational Journal of Disaster Risk Science
From 10 to 15 April 2025, China experienced a rare persistent extreme wind-dust compound disaster that swept from north to south. Based on observational data, historical disaster records, and situations of various exposed elements, this study analyzed ...
Gangfeng Zhang   +12 more
doaj   +1 more source

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