Results 41 to 50 of about 2,581,564 (248)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
A Simple Model to Predict Machined Depth and Surface Profile for Picosecond Laser Surface Texturing
A simple mathematical model was developed to predict the machined depth and surface profile in laser surface texturing of micro-channels using a picosecond laser. Fabrication of micro-craters with pulse trains of different numbers was initially performed.
Jieyu Xian +5 more
doaj +1 more source
The density profile and Gibbs adsorption of a near-critical fluid confined between two identical planar walls is studied by means of Monte Carlo simulation and by density functional theory for a Lennard-Jones fluid.
A. Maciołek +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
High-precision surface defect detection in manufacturing often relies on laser triangulation profilometric sensors for detailed surface measurements, providing detailed and accurate surface measurements over a line. Accurate motion between the sensor and
Sara Roos-Hoefgeest +3 more
doaj +1 more source
Gas-Surface Dynamics and Profile Evolution during Etching of Silicon [PDF]
Scattering of energetic F atoms on a fluorinated Si surface is studied by molecular beam methods. The energy transfer closely follows hard-sphere collision kinematics.
Anderson, C. M. +5 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Investigation of the Geometry of Metal Tube Walls after Necking in Uniaxial Tension
: In order to characterize the deformation and true stress–strain relation of metal tubes, the geometry of tube walls after necking in uniaxial tension need to be determined. The paper investigated the necking process of metal tube.
Chong Li +3 more
doaj +1 more source
Measurement of surface roughness slope [PDF]
Instrument, consisting of isolator, differentiator, absolute value circuit, and integrator, uses output signal from surface texture analyzer profile-amplifier to calculate surface roughness slope. Calculations provide accurate, instantaneous value of the
Cassidy, J. F., Donner, H. C.
core +1 more source

