Results 91 to 100 of about 5,012,413 (327)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

On the Convergence of the Electronic Structure Properties of the FCC Americium (001) Surface

, 2006
Electronic and magnetic properties of the fcc Americium (001) surface have been investigated via full-potential all-electron density-functional electronic structure calculations at both scalar and fully relativistic levels. Effects of various theoretical
Asok K. Ray, Bartra, Blaha, Blöchl, Boettger, Boettger, Boettger, Boettger, Cox, Da Gao, Dai, Dreialer, Eriksson, Feibelman, Freeman, Gao, Gao, Gao, Gay, Ghosh, Gong, Gong, Gouder, Griveau, Heathman, Hohenberg, Huda, Huda, Huda, Huda, Huda, Huda, Huray, Jeanloz, Johansson, Johansson, Johansson, Koelling, Kohn, Kotliar, Kutepov, Lander, Lindbaum, Link, MacDonnald, Madsen, Martensson, Mola, Naegele, Perdew, Perdew, Perdew, Petersen, Pénicaud, Ray, Ray, Savrasov, Savrasov, Schulte, Schwarz, Shick, Singh, Skriver, Smith, Soderlind, Stjöstedt, Wei, Wu   +67 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Surface Properties and Osteoblastic Cytocompatibility of Two Blasted and Acid-Etched Titanium Implant Systems with Distinct Microtopography

eJournal of Oral Maxillofacial Research, 2012
Objectives: The aim of this study is to compare two commercially available screw-type sandblasted and acid-etched (SLA) Ti implant systems from Eckermann Laboratorium S.L., with similar geometry and distinct microtopography, regarding surface properties ...
Pedro Mesquita, Pedro de Sousa Gomes, Paula Sampaio, Gintaras Juodzbalys, Américo Afonso, Maria Helena Fernandes   +5 more
doaj  

Surface properties of ocean fronts [PDF]

Background information on oceanic fronts is presented and the results of several models which were developed to study the dynamics of oceanic fronts and their effects on various surface properties are described.
Hubert, W. E., Wolff, P. M.
core   +1 more source

On the properties of surface reconstructed silicon nanowires

, 2004
We study by means of density-functional calculations the role of lateral surface reconstructions in determining the electrical properties of silicon nanowires.
Rurali R, Soler J M, Wulff G
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

A Study of the Coefficient of Friction in Steel Sheets Forming

Metals, 2019
The aim of this paper was to compare the tribological properties of a deep drawing quality steel sheet using the three commonly used friction tests, i.e., the strip drawing test, draw bead test, and bending under tension test. All tests have been carried
Tomasz Trzepiecinski
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Detecting hydrogen-containing contaminants on metal surfaces [PDF]

, 1969
Spark emission spectroscopy analyzes surface contamination of metals. This technique controls the quality of surface preparations and is useful in fundamental investigations of surface properties of ...
Grove, E. L., Losele, W. A.
core   +1 more source