Results 111 to 120 of about 4,957,392 (326)
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Deep Learning Regressors of Surface Properties from Atomic Force Microscopy Nanoindentations
Atomic force microscopy (AFM) is a powerful technique to study the nanomechanical properties of a wide range of materials at the piconewton level. AFM force–indentation curves can be fitted with appropriate contact models, enabling the determination of ...
Luís R. L. Pacheco +2 more
doaj +1 more source
Properties of Shepard's surfaces [PDF]
Barnhill, R.E., Dube, R.P., Little, F.F.
openaire +3 more sources
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Background: This study compared and analyzed the surface properties, including gloss, Vickers hardness, surface roughness, surface morphology, and color stability, of various aesthetic restorative materials subjected to in-office tooth bleaching ...
Ji-Won Choi, Song-Yi Yang
doaj +1 more source
Adsorption on a surface with varying properties
33 pages with 11 figures, REVTeX 4; Correction in relation (9) and in the subsequent expressions connected with this quantity. These corrections do not affect the main qualitative conclusions of the paper. Addition of Application B: analysis of the kinetics of adsorption in the special case of slow and fast variables describing the ...
openaire +3 more sources
Physical properties of surfaces - III—The surface temperature of sliding metals - The temperature of lubricated surfaces [PDF]
Frank Philip Bowden, K. E. W. Ridler
openalex +1 more source
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source

