Results 81 to 90 of about 4,007,124 (352)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Modelling and simulation of the dynamic cutting process and surface topography generation in nano/micro cutting [PDF]

open access: yes, 2008
In nano/micro cutting process, the surface quality is heavily dependent on all the dynamic factors in machining including those from the material, tooling, cutting parameters, servo accuracy, mechanical structure deformation, and non-linear factors as ...
Cheng, K, Zhou, L
core  

Highly-ordered graphene for two dimensional electronics

open access: yes, 2006
With expanding interest in graphene-based electronics, it is crucial that high quality graphene films be grown. Sublimation of Si from the 4H-SiC(0001) Si-terminated) surface in ultrahigh vacuum is a demonstrated method to produce epitaxial graphene ...
Berger, C.   +9 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

WATER QUALITY INDICES FOR THE MANAGEMENT OF SURFACE WATER QUALITY

open access: yesWater Science and Technology, 1988
The need for a simple, objective and reproducible numeric scale to represent water quality in terms that all types of user will accept has been apparent for the last twenty years. Subjective classifications of water quality have been made, but they are seldom reproducible and lack sensitivity.
D. H. Newsome, M. A. House
openaire   +1 more source

Influence of the surface termination to the point imaging by a photonic crystal slab with negative refraction

open access: yes, 2004
Point imaging by a photonic crystal slab due to the negative refraction is studied theoretically. By investigating the transfer function of the imaging system, the influence of the surface termination to the imaging quality is analyzed.
He, Sailing   +3 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Precision CNC Machining of Femoral Component of Knee Implant: A Case Study

open access: yesMachines, 2018
The design and manufacturing of medical implants constitutes an active and highly important field of research, both from a medical and an engineering point of view.
Angelos P. Markopoulos   +3 more
doaj   +1 more source

Source attribution of ozone in Southeast Texas before and after the Deepwater Horizon accident using satellite, sonde, surface monitor, and air mass trajectory data [PDF]

open access: yes, 2010
Since the summer of 2004, over 300 ozonesondes have been launched from Rice University (29.7 N, 95.4 W) or the University of Houston (29.7 N, 95.3 W), each \u3c 5 km from downtown Houston.
Haman, Christine   +5 more
core   +2 more sources

Scanning Tunneling Microscopy studies on CeCoIn$_5$ and CeIrIn$_5$

open access: yes, 2010
High--quality single crystals of the heavy fermion superconductors CeCoIn$_5$ and CeIrIn$_5$ have been studied by means of low--temperature Scanning Tunneling Microscopy.
Dynes   +25 more
core   +1 more source

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