Results 41 to 50 of about 5,084,579 (305)

Research on the Influence of Shallow Buried Tunnel Crossing on the Stability of Overlying Frame Structure Building

Journal of Marine Science and Engineering
The land section of the Huangdao end of the Jiaozhou Bay Second Submarine Tunnel is extensively underlain by the Quaternary Loose Accumulation Layer. The tunnel passes through a weathered granite fracture zone with well-developed rock joints beneath the ...
Bo Wang, Suizi Jia, Mingyi Han, Jingkai Qu, Huimin Gong, Chao Lu, Ziming Qu   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Characterisation of the supply-settlement relationship for Semibalanus balanoides (L.) along a wave swept coast in Fife, East Scotland [PDF]

, 2007
This thesis describes the results of a three year study which collected larvae of the acorn barnacles Semibalanus balanoides on a rocky coastline in Fife, East Scotland. The nauplii larvae of S.
Phelan, Patrick J. C.
core   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Sandy aquifer collapse mechanism and accident treatment of the Qingdao metro tunnel

Frontiers in Earth Science, 2023
The tunnel collapse occurred during the construction of the Qingdao Metro Line Ⅰ, resulting in a pit measuring approximately 10 m in diameter and 7 m in depth on the ground surface.
Liwei Zhang, Zaiquan Wang, Weiguo Zhang, Sijia Liu   +3 more
doaj   +1 more source

Shallow tunneling's impact on surface settlements

The Journal of Engineering and Exact Sciences
The research described in this paper deals with the impact of shallow tunneling on surface settlements in urban areas. The study focuses on carrying out a numerical analysis and a parametric geotechnical study to investigate the effects of tunnel excavation on the surface ground, particularly with regard to distortion and potential damage to structures
Mohamed Djenane, Kamel Bezih
openaire   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Surface settlements caused by shield construction of gas-bearing soils based on column hole shrinkage theory

Yantu gongcheng xuebao
Relying on the actual project of Hangzhou Metro Tangqing Line shield crossing the gas-bearing stratum, the column hole shrinkage theory is modified, and the formula for calculating the surface settlement caused by the construction of the shield structure
DING Zhi 1, 2, 3, PENG Shaojie 1, ZHANG Xiao 1, XU Jiaoming 2, WEI Xinjiang 2
doaj   +1 more source

Numerical modeling of tunneling induced ground deformation and its control [PDF]

International Journal of Mining and Geo-Engineering, 2016
Tunnelling through cities underlain by soft soil, commonly associated with soil movement around the tunnels and subsequent surface settlement. The predication of ground movement during the tunnelling and optimum support pressure could be based on ...
V B Maji, Abite Adugna
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source